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Protein Alignment CG9098 and Sh2d3c

DIOPT Version :9

Sequence 1:	NP_608979.2	Gene:	CG9098 / 33840	FlyBaseID:	FBgn0031762	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_038809.1	Gene:	Sh2d3c / 27387	MGIID:	1351631	Length:	854	Species:	Mus musculus

Alignment Length:	879	Identity:	266/879 - (30%)
Similarity:	400/879 - (45%)	Gaps:	164/879 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 RAKRRQSM-NLEAMSSAPRAVPRRKNSCPLVYLGENPQDM-----AGSG------DSGPGVITTK 154
            :|:::|:: ..:.:|.....|.||        |.| |.|:     ||.|      |:.|..:...
Mouse    87 KAQKQQAVQKAQEVSRESHLVSRR--------LPE-PPDLEAAKEAGEGTEALLEDTAPSAVEVD 142

  Fly   155 SGKVLKQLTFD-ETSTIYEELRPRSKCNSPHWAIEDSRMEGYGSSNATTPLATAQPSPSEQQEAI 218
            ..:.|:.||.| |...:..::.|.      ..|.|......|...:....:..:.|.
Mouse   143 PMRELEDLTVDTEKEQVPGDVSPE------RTAAELEAAGDYVKFSKEKYILDSSPE-------- 193

  Fly   219 ALKKALEWELSLDARELRSHAWYHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVL 283
            .|.|.||.||.|.:.:|||||||||.:||:.:|.:|||.||||:||..:...:|||:||.....|
Mouse   194 KLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWHNQAL 258

  Fly   284 HFVLNKLVLQPETVYERVQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQFPCNRTYPLSF- 347
            ||.:||:|::....|..::|.||:::||.||.|:.::|||.|.:|..|||:|..|.|||:||.:
Mouse   259 HFKINKVVVKAGESYTHIRYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYL 323

  Fly   348 ---YGHKIVGNQLHTQMLAGLRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQQQLSPMAGSPA 409
               ||..              :|.|...||...:|:.|:.|.
Mouse   324 EASYGLS--------------QGSSKTASPASPSGSKGSHMK----------------------- 351

  Fly   410 SPHCSPPRARREVPPPPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQLQMQELENGNGNGIMRF 474
                     ||.:.....|...|..||.. .|....|....:.::...|.|.::.:.:
Mouse   352 ---------RRSITMTDGLTTDKVTRSDG-CPNSTSLPHPRDSIRNCALSMDQIPDLH------- 399

  Fly   475 QTIARCNPTSEQHLESKFTT----HS-LPRPNTSAAHALRQQAVARISSLARNCSLDSP-----S 529
               :..:|.||......::|    |: ...|:|||..|   ..|||.||..:.|..::|     |
Mouse   400 ---SPLSPISESPSSPAYSTVTRVHAPSATPSTSAQPA---SPVARRSSEPQLCPGNTPKPPGES 458

  Fly   530 DSRPPSPPPKP--RKEPMAAVLAYQASGSDSGN---------GSGDSALGDACEASVQRGVIIKN 583
            |..|.:.|...  :..|..::.:|  |..|||:         ||.:.|.|:....:  ||...:.
Mouse   459 DRAPHASPSHTLCKASPSPSLSSY--SDPDSGHYCQLQPPVRGSREQAAGETPRKA--RGSGERQ 519

  Fly   584 PRFMTTSVSNGTL-KSFTEFDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDA 647
            ...:...||:|.. |:||               :..|:..|.|:...|.:.|:|. ||:||:...
Mouse   520 KELLENGVSDGEWGKTFT---------------VPVVEATSSFNLATFQSQLIPK-ENRPLEVAL 568

  Fly   648 LNTFKMMLLETGPKLLAEHITRID--IALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIER 710
            |...|.:|.|...:.||.|:|::|  :|..|......:.......|:||||||||:..|.|::||
Mouse   569 LRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLER 633

  Fly   711 TQCIKLMVAVTILTCQTDL-DRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAW 774
            ...:.:|:||.||.|.... :||.||.|.||:|.|.:..:||:|.|.|:|..|.|.||.:|:|.|
Mouse   634 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALEMAQISRLEQTW 698

  Fly   775 HILRQQYTDSAFTFEAKLRPTLSIMNEA-SNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDR 838
            ..|||::|:.|..:|.||:|.|..:||. ..|...|||.||||.:..|::           .|..
Mouse   699 MTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPFITLLE-----------CDSA 752

  Fly   839 PALYHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADAFRT 903
            ||   ....||.|  .:.|:.:...||:|:|....:..||..||::.|:....| .||| :.|.|
Mouse   753 PA---EGPEPWGS--TEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQAR-PELL-EVFST 810

  Fly   904 EFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADK 937
            ||.::.||||.||.:....|:.|.:||||.::.|
Mouse   811 EFQMRLLWGSQGANSSQAWRYEKFDKVLTALSHK 844

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.