Protein Alignment CG9098 and sh2d3a

DIOPT Version :9

• Sequence 1: NP_608979.2
• Gene: CG9098 / 33840
• FlyBaseID: FBgn0031762
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: XP_002665109.4
• Gene: sh2d3a / 100331568
• ZFINID: ZDB-GENE-140401-1
• Length: 806
• Species: Danio rerio
• Alignment Length: 946
• Identity: 254/946 - (26%)
• Similarity: 401/946 - (42%)
• Gaps: 208/946 - (21%)

  Fly    47 SISEWLDLLELQQYEGNLQ-EFSTVDDVVDITDKELKQFGVRGA-HRQRMVNSLLGVRAKRRQSM 109
            |||.||:.:.|.||...|: ::..::.:..:|:::|:..||... ||.:::..|      ::|..
Zfish     5 SISRWLNRIGLPQYTSALEKQYYGLEGLQSVTEEDLRLMGVEDPDHRVKILAEL------QKQQC 63

  Fly   110 NLEAMSSAPRAVPRRKNSCPLVYLGENPQDMAGSGDSGPGVITTKSGKVLKQLTFDETSTIYEEL 174
            :.|             |:|.                  .|.::::....||:......| |...|
Zfish    64 DTE-------------NNCT------------------TGTMSSRHSLDLKRTDLFRHS-IIPRL 96

  Fly   175 RPRSKCNSPHWAIEDSRMEGYGSSNATTP---LATAQPSP--SEQQEAIALKKALEWELSLDARE 234
            |.|.|..|.  :....|.|.:...:...|   ..||..|.  |..::..||||.||.||.|...:
Zfish    97 RRRDKRVSA--SCIQLRPEDHAPCSKHKPRRRSVTAFISQVFSGLRDMDALKKELEEELKLSTED 159

  Fly   235 LRSHAWYHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYE 299
            |||||||||.|.|:.||:::.|:|:|||||.::...:|||:|..|...:||.:.::.|:|:..|.
Zfish   160 LRSHAWYHGQLQREAAEQLLGRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIRITLRPKQGYT 224

  Fly   300 RVQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQFPCNRTYPLSFYGHKIVGNQLHTQMLAG 364
            |..:|||.|.||.:|.||.|:||..:|||.::||:|..|..||.||     :|:..:
Zfish   225 RELFQFENDQFDNIPALIRFHVGGRRPISHSTGAVIFQPITRTLPL-----RIISER-------- 276

  Fly   365 LRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQQQLSPMAGSPASPHCSPPRARREVPPPPRLP 429
                                                   .|...:|.|.
Zfish   277 ---------------------------------------QAARSSSAHL---------------- 286

  Fly   430 CKKQQRSQSLTPAQA-MLVSNINKLQEQQLQMQELENGNGNGIMRFQTIARCNPTSEQHLESK-- 491
            .:.|.:.:||:.:|. .|..|.|.|.....|...||......:...|:.:.......|..:|:
Zfish   287 MRSQSKRRSLSSSQKDTLQVNTNNLLRSGSQPANLETVGRPFLQSAQSDSNLRTGVPQSCQSQDS 351

  Fly   492 --------FTTHSLP--RPNTSAAHALRQQAVARISSLARNCSLDSPSDSRPPSPPPKPRKEPMA 546
                    |.|.|.|  .|..|.|....|.|:. :|.|   |..|....||   .||||.:..:.
Zfish   352 DPAPVSPVFRTGSEPVLSPAASCATPAGQSALG-VSPL---CGSDGQLHSR---APPKPLRISII 409

  Fly   547 AVLAYQASGSDSGNGSGDSA---------LGDACEASVQRGVIIKNPRFMTTSVSNGTL------ 596
            .........||..:..|:..         .|.|.....|........|.  |..|.|.|
Zfish   410 FSPTQTDPESDPADVYGELVPQVPITMLPKGHAARLRAQEQKWKSRARL--TDTSFGFLEAQRVE 472

  Fly   597 --------KSFTEFDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKM 653
                    :|.:|   |..||..:.....:.:|:|.|..:.|.:||||. .|:|||...|...|.
Zfish   473 EERVEEERRSGSE---LQQEERDWCFERPQTETSSCFRLDEFRSLLLPD-NNRPLDQSVLPKVKE 533

  Fly   654 MLLETGPKLLAEHITRID--IALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIERTQCIKL 716
            :|.:|..:..|.|:..::  :|......:.::......:||||:|||||...|:|::||...:.|
Zfish   534 LLTQTDARTTALHMLSVNCQVARVTGVTAEQKRIMGVETGLELVTLPHGGQLRQDLLERHHALAL 598

  Fly   717 MVAVTILTCQ-TDLDRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQ 780
            .:||.:|.|. |...||.:|.:.||:|.|.:....:|:||.|:|..|.|.|:.:|:..|..||:.
Zfish   599 GIAVDLLGCTGTVGQRATVLHRIIQLAQELRNTTHDLYGFSAVMKALEMPQVVRLEMTWRALRRN 663

  Fly   781 YTDSAFTFEAKLRPTLSIMNE-----ASNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDRPA 840
            :||||.|||..|:|.:..:||     .|.|    .::||:|        |::.:     ::...|
Zfish   664 HTDSAVTFEKSLKPFMKALNEGDDSVVSGP----LSLPHLL--------PLLRL-----MEGEDA 711

  Fly   841 LYHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRK----NAKIILEDASPRLDELLADAF 901
            :..|          |.|..:.:..|.::|    |..|:.:    :|..:|......:.||| :.|
Zfish   712 VETT----------DRGCLLLYNLLQSAR----NATLHARDCTLHAHSLLSAGWEPVPELL-EVF 761

  Fly   902 RTEFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADK 937
            :|||.::..||.:||.|:.::|..|.:::|.|::.|
Zfish   762 QTEFALRLFWGQTGAKAERKERFAKFDRILELLSYK 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9098	NP_608979.2	SAM_1	43..102	CDD:278937	16/56 (29%)
		SAM	47..103	CDD:197735	16/57 (28%)
		SH2_BCAR3	233..367	CDD:198200	55/133 (41%)
		RasGEF	660..>797	CDD:295324	50/139 (36%)
sh2d3a	XP_002665109.4	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28HJ9
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49555
OrthoDB	1	1.010	-	-		D138275at2759
OrthoFinder	1	1.000	-	-		FOG0003062
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810