DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL16

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001320597.1	Gene:	BGAL16 / 844078	AraportID:	AT1G77410	Length:	820	Species:	Arabidopsis thaliana

Alignment Length:	761	Identity:	179/761 - (23%)
Similarity:	292/761 - (38%)	Gaps:	218/761 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LIIAVMALTVGLCVGLSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSR 82
            :.:.:||:.|      :||.        ..:.::..:.::||:.....|||.||.|:.|:.|.|.
plant     9 VFLVLMAVIV------AGDV--------ANVTYDGRSLIIDGEHKILFSGSIHYTRSTPQMWPSL 59

  Fly    83 LRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICAERDNG 147
            :...::.|::.:||||.|::|.|..|::::.|..|:|||::..:....|:.||.||:|..|...|
plant    60 IAKAKSGGIDVVDTYVFWNVHEPQQGQFDFSGSRDIVKFIKEVKNHGLYVCLRIGPFIQGEWSYG 124

  Fly   148 GLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRL---QHLFVGNGGKIIM-----VQVENEY 204
            |||.||. ....|..||::..:...: |.||:::.:|   ::|:...||.||:     .|:||||
plant   125 GLPFWLH-NVQGIVFRTDNEPFKYHM-KRYAKMIVKLMKSENLYASQGGPIILSQLCAKQIENEY 187

  Fly   205 GDYACDHDYLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKIENVFATTDFGIDRINEIDKIWAM 269
            |...      ...|.|.:.||...|.| .|::                 |.|:.        |.|
plant   188 GMVG------RAFRQEGKSYVKWTAKL-AVEL-----------------DTGVP--------WVM 220

  Fly   270 LRALQPTGPLVNS-------EFYPG---------WLTHWQ-------EQNQRRDGQEVANALRTI 311
            .:......||||:       |.:.|         |..:|.       |:...|..:::|..:...
plant   221 CKQDDAPDPLVNACNGRQCGETFKGPNSPNKPAIWTENWTSFYQTYGEEPLIRSAEDIAFHVALF 285

  Fly   312 LSYNAS-VNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAG------------- 362
            ::.|.| ||.||:.||||||..|....           ||||...|.:||.|
plant   286 IAKNGSFVNYYMYHGGTNFGRNASQFV-----------ITSYYDQAPLDEYGLLRQPKWGHLKEL 339

  Fly   363 -------------GVTT---------------KYNLVKAVI----------------GEFLPLPE 383
                         |:.|               |.||..|::                ....|...
plant   340 HAAVKLCEEPLLSGLQTTISLGKLQTAFVFGKKANLCAAILVNQDKCESTVQFRNSSYRLSPKSV 404

  Fly   384 ITLNPAKRLAYGRVELTPKLTLLSTEGRAALSKGDPVESIKP--KTFEELDLYSGLVL------- 439
            ..|...|.:|:...::..:....:.:.|..||.....|....  .:|.|..:.|..:|
plant   405 SVLPDCKNVAFNTAKVNAQYNTRTRKARQNLSSPQMWEEFTETVPSFSETSIRSESLLEHMNTTQ 469

  Fly   440 -------YETELPSMDLDPALLKIDQINDRAHVFVDQELVGTLSREAQIYSLPLSKGWG-----S 492
                   ..|.....:..|::||::.:....|.||:...:|::....:.:...|.|...     :
plant   470 DTSDYLWQTTRFQQSEGAPSVLKVNHLGHALHAFVNGRFIGSMHGTFKAHRFLLEKNMSLNNGTN 534

  Fly   493 TLQLL-----VENQGRVNFYISNDTKGIFGEVSLQLHNGGY------------LPLENWRSTAFP 540
            .|.||     :.|.|      ::..:.:.|..|:::.||.|            :.|:..:...:.
plant   535 NLALLSVMVGLPNSG------AHLERRVVGSRSVKIWNGRYQLYFNNYSWGYQVGLKGEKFHVYT 593

  Fly   541 LEQSAVELWRREHTDEKALDPLLARQRILRNGPILYTGSLTVTEVGD-TYLNMAGWGKGVAYVNG 604
            .:.||...| :::.|.|: .||           ..|..|....|..| ..||:...|||.|:|||
plant   594 EDGSAKVQW-KQYRDSKS-QPL-----------TWYKASFDTPEGEDPVALNLGSMGKGEAWVNG 645

  Fly   605 FNLGRYW---------PVAGPQVTLYVPNEILKVGENSLVILEYQR 641
            .::||||         |   .|:..::|...||...|.|||||.:|
plant   646 QSIGRYWVSFHTYKGNP---SQIWYHIPRSFLKPNSNLLVILEEER 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	105/410 (26%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	25/76 (33%)
BGAL16	NP_001320597.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820