DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL10

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_201186.1	Gene:	BGAL10 / 836501	AraportID:	AT5G63810	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	787	Identity:	195/787 - (24%)
Similarity:	305/787 - (38%)	Gaps:	211/787 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NRKLTMAVSGCLIIAVMALTVGLCVGLSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHY 71
            ||..|.:::...|:.||......         ...|....:.||.:.|  :..:....:|.:.||
plant     2 NRVTTESIASTAILVVMVFLFSW---------RSIEAANVSYDHRSLT--IGNRRQLIISAAIHY 55

  Fly    72 FRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRP 136
            .|:||..|.|.::|.:..|.||:::||.|:.|.|..|:|.:.|..::|||::|.|:...::|||.
plant    56 PRSVPAMWPSLVQTAKEGGCNAIESYVFWNGHEPSPGKYYFGGRYNIVKFIKIVQQAGMHMILRI 120

  Fly   137 GPYICAERDNGGLPHWLFTKYPSIKMRTNDP--NYISEVGKWYAELMPRLQHLFVGNGGKIIMVQ 199
            ||::.||.:.||:|.||.....::....|:|  :|:.....:...|: :.:.||...||.||:.|
plant   121 GPFVAAEWNYGGVPVWLHYVPGTVFRADNEPWKHYMESFTTYIVNLL-KQEKLFAPQGGPIILSQ 184

  Fly   200 VENEYGDYACDHD-----YLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKIE---NVFATTD-F 255
            ||||||.|..|:.     |..|        .:..|:...:.:|  .|.|.:.:   .|.:|.: |
plant   185 VENEYGYYEKDYGEGGKRYAQW--------SASMAVSQNIGVP--WMMCQQWDAPPTVISTCNGF 239

  Fly   256 GIDRI--NEIDKIWAMLRALQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTILSYNASV 318
            ..|:.  |..||            |.:.:|.:|||...:..::..|..::||.::........||
plant   240 YCDQFTPNTPDK------------PKIWTENWPGWFKTFGGRDPHRPAEDVAYSVARFFGKGGSV 292

  Fly   319 -NLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAG---------------GVTTK 367
             |.||:.||||||.|:|..:          ..|||||:|.:||.|               .:...
plant   293 HNYYMYHGGTNFGRTSGGPF----------ITTSYDYEAPIDEYGLPRLPKWGHLKDLHKAIMLS 347

  Fly   368 YNLV--------------------------------------KAVI----GEFLP------LPEI 384
            .||:                                      |||:    ...||      ||:.
plant   348 ENLLISGEHQNFTLGHSLEADVYTDSSGTCAAFLSNLDDKNDKAVMFRNTSYHLPAWSVSILPDC 412

  Fly   385 ---TLNPAKRLA-YGRVELTP---------KLTLLSTE----GRAALSKGDPVESIK--PKTFEE 430
               ..|.||..: ..:||:.|         |..:.|.:    |.|...|.:.|:.|.  ..|.:.
plant   413 KTEVFNTAKVTSKSSKVEMLPEDLKSSSGLKWEVFSEKPGIWGAADFVKNELVDHINTTKDTTDY 477

  Fly   431 LDLYSGLVLYETELPSMDLDPALLKIDQINDRAHVFVDQELVGTLSREAQIYSLPLS-----KGW 490
            |...:.:.:.|.|.........:|.|:......|||:::|.:||.:.........|.     |..
plant   478 LWYTTSITVSENEAFLKKGSSPVLFIESKGHTLHVFINKEYLGTATGNGTHVPFKLKKPVALKAG 542

  Fly   491 GSTLQLLVENQGRVNFYISNDTKGIFGE--------VSLQLHNGGYLPLEN--WRSTAFPLEQSA 545
            .:.:.||....|..|       .|.|.|        ||::..|.|.|.|.|  | |....:|...
plant   543 ENNIDLLSMTVGLAN-------AGSFYEWVGAGLTSVSIKGFNKGTLNLTNSKW-SYKLGVEGEH 599

  Fly   546 VELWRREH--------TDEKALDPLLARQRILRNGPILYTGSLTVTEVGDTYLNMAGWGKGVAYV 602
            :||::..:        |.:......|...:::...|   :||   ..||   |:|...|||:|::
plant   600 LELFKPGNSGAVKWTVTTKPPKKQPLTWYKVVIEPP---SGS---EPVG---LDMISMGKGMAWL 655

  Fly   603 NGFNLGRYWP---------------------------VAG----PQVTLYVPNEILKVGENSLVI 636
            ||..:|||||                           :.|    .|...:||....|...|.|||
plant   656 NGEEIGRYWPRIARKNSPNDECVKECDYRGKFMPDKCLTGCGEPSQRWYHVPRSWFKSSGNELVI 720

  Fly   637 LEYQRAN 643
            .|.:..|
plant   721 FEEKGGN 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	105/392 (27%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	26/97 (27%)
BGAL10	NP_201186.1	PLN03059	14..741	CDD:166698	192/775 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820