DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL3

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_568001.1	Gene:	BGAL3 / 829788	AraportID:	AT4G36360	Length:	856	Species:	Arabidopsis thaliana

Alignment Length:	796	Identity:	197/796 - (24%)
Similarity:	303/796 - (38%)	Gaps:	243/796 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGCRRNRKLTMAVSGCLIIAVMALTVGLCVGLSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVS 66
            :|...:|.:.....|.||:.|..:..|:                 |.|.:|  .:::||.....|
plant     6 TGDSASRLILWFCLGFLILGVGFVQCGV-----------------TYDRKA--LLINGQRRILFS 51

  Fly    67 GSFHYFRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFY 131
            ||.||.|:.|:.|...::..:..|::.::|||.|:||.|..|:|::||..|:|:|::...:...|
plant    52 GSIHYPRSTPDMWEDLIQKAKDGGIDVIETYVFWNLHEPSPGKYDFEGRNDLVRFVKTIHKAGLY 116

  Fly   132 IILRPGPYICAERDNGGLPHWLFTKY-PSIKMRT-NDPNYISEVGKWYAELMPRL---QHLFVGN 191
            ..||.|||:|||.:.||.|.||  || |.|..|| |:|  .....|.:.|.:..|   ::||...
plant   117 AHLRIGPYVCAEWNFGGFPVWL--KYVPGISFRTDNEP--FKRAMKGFTERIVELMKSENLFESQ 177

  Fly   192 GGKIIMVQVENEYGDY-----ACDHDYLNWLRDETEKYVSGKALLFTV-----------DIPNEK 240
            ||.||:.|:|||||..     |..|:|:.|         :.|..:.|.           |.|:..
plant   178 GGPIILSQIENEYGRQGQLLGAEGHNYMTW---------AAKMAIATETGVPWVMCKEDDAPDPV 233

  Fly   241 M-SCGKIENVFATTDFGIDRINEIDKIWAMLRALQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEV 304
            : :|    |.|....|..::               |..||:.:|.:.||.|.:......|..|::
plant   234 INTC----NGFYCDSFAPNK---------------PYKPLIWTEAWSGWFTEFGGPMHHRPVQDL 279

  Fly   305 A-NALRTILSYNASVNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAGGV-TTK 367
            | ...|.|....:.||.||:.||||||.|||..:          ..|||||||.:||.|.: ..|
plant   280 AFGVARFIQKGGSFVNYYMYHGGTNFGRTAGGPF----------VTTSYDYDAPIDEYGLIRQPK 334

  Fly   368 YNLVK----------------------------------------AVIGEF-------------- 378
            |..:|                                        |.:..:
plant   335 YGHLKELHRAIKMCEKALVSADPVVTSIGNKQQAHVYSAESGDCSAFLANYDTESAARVLFNNVH 399

  Fly   379 --LPLPEITLNPAKRLAY---GRVEL-TPKLTLLSTEGRAALSKGDPVESI--------KPKTF- 428
              ||...|::.|..|.|.   .:|.: |.::.:|.|:     :|....||.        ...||
plant   400 YNLPPWSISILPDCRNAVFNTAKVGVQTSQMEMLPTD-----TKNFQWESYLEDLSSLDDSSTFT 459

  Fly   429 -----EELDLYSGLVLYETELPSMDLD-----------PALLKIDQINDRAHVFVDQELVGTLSR 477
                 |::::......|...:.|:|:.           |.|: |.......|:||:.:|.|:
plant   460 THGLLEQINVTRDTSDYLWYMTSVDIGDSESFLHGGELPTLI-IQSTGHAVHIFVNGQLSGS--- 520

  Fly   478 EAQIYSLPLSKGWGSTLQLLVENQGRVNFYISNDTKGIFGEVSLQLHN-GGYLPLENWRS----- 536
                       .:|:........||::|.:...:...:. .|::.|.| ||:  .|:|.:
plant   521 -----------AFGTRQNRRFTYQGKINLHSGTNRIALL-SVAVGLPNVGGH--FESWNTGILGP 571

  Fly   537 -TAFPLEQSAVELWRREHTDEKALDPLLARQRILRNGPIL--YTGSLTVTEV-----GDTY---- 589
             ....|.|..::|..::.|.:..|...........|.|.:  ...||||.:.     ..||
plant   572 VALHGLSQGKMDLSWQKWTYQVGLKGEAMNLAFPTNTPSIGWMDASLTVQKPQPLTWHKTYFDAP 636

  Fly   590 -------LNMAGWGKGVAYVNGFNLGRYWPVAG-------------------------PQVTLYV 622
                   |:|.|.|||..:|||.::||||....                         .|...:|
plant   637 EGNEPLALDMEGMGKGQIWVNGESIGRYWTAFATGDCSHCSYTGTYKPNKCQTGCGQPTQRWYHV 701

  Fly   623 PNEILKVGENSLVILE 638
            |...||..:|.|||.|
plant   702 PRAWLKPSQNLLVIFE 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	113/385 (29%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	29/109 (27%)
BGAL3	NP_568001.1	PLN03059	9..846	CDD:166698	196/793 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820