DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL11

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_567973.1	Gene:	BGAL11 / 829653	AraportID:	AT4G35010	Length:	845	Species:	Arabidopsis thaliana

Alignment Length:	802	Identity:	196/802 - (24%)
Similarity:	314/802 - (39%)	Gaps:	233/802 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LIIAVMALTVGLCVGLSGDTDA-PEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRS 81
            |:.||:.:.:......:...|| .:::....:.::..:.::||:.....|||.||.|:.||.|.|
plant    10 LLTAVLVVLLSSSSSFAAKKDAKKKKKSNKEVTYDGTSLIIDGKRELLYSGSIHYPRSTPEMWPS 74

  Fly    82 RLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICAERDN 146
            .::..:..|||.:.|||.|::|.|..|::|:.|.||:|||:::.|:...|:.||.||:|.||..:
plant    75 IIKRAKQGGLNTIQTYVFWNVHEPQQGKFNFSGRADLVKFIKLIQKNGMYVTLRLGPFIQAEWTH 139

  Fly   147 GGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRL--QHLFVGNGGKIIMVQVENEYG--DY 207
            ||||:|| .:.|.|..||::..:.....::...::.::  :.||...||.||:.|:||||.  ..
plant   140 GGLPYWL-REVPGIFFRTDNKQFKEHTERYVRMILDKMKEERLFASQGGPIILGQIENEYSAVQR 203

  Fly   208 ACDHDYLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKIENVFATTDFGIDRINEIDKIWAMLRA 272
            |...|.||::     |:.|                     |:..:...||.        |.|.:.
plant   204 AYKQDGLNYI-----KWAS---------------------NLVDSMKLGIP--------WVMCKQ 234

  Fly   273 LQPTGPLVNS-------EFYPG---------WLTHWQEQNQ-------RRDGQEVANALRTILSY 314
            .....|::|:       :.:||         |..:|..|.:       :|..:::|.::....|.
plant   235 NDAPDPMINACNGRHCGDTFPGPNRENKPSLWTENWTTQFRVFGDPPTQRSVEDIAYSVARFFSK 299

  Fly   315 NAS-VNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAG-GVTTKYNLVKAVIGE 377
            |.: ||.||:.||||||.|: |:|          ..|.|..||.:||.| ....||..:|.:
plant   300 NGTHVNYYMYHGGTNFGRTS-AHY----------VTTRYYDDAPLDEYGLEKEPKYGHLKHL--- 350

  Fly   378 FLPLPEITLNPAKR-LAYG--RVELTPKLTLL------STEGRAAL---SKGDPVESIK------ 424
                 ...||..|: |.:|  :.|...|.|.:      .|:..||.   :..:..|:||
plant   351 -----HNALNLCKKPLLWGQPKTEKPGKDTEIRYYEQPGTKTCAAFLANNNTEAAETIKFKGREY 410

  Fly   425 ---PKTFEELDLYSGLVLYETELPSMDLDPALLKIDQINDR--AHVFVD---QELVGTLSREAQI 481
               |::...|.....:|....::.|.......:|..:.|.:  ..||.:   .:|.|......::
plant   411 VIAPRSISILPDCKTVVYNTAQIVSQHTSRNFMKSKKANKKFDFKVFTETLPSKLEGNSYIPVEL 475

  Fly   482 YSLPLSK---GWGSTLQLLVENQGRVNFYISND----TKGI-----FGEVSLQLH---NGGYLPL 531
            |.|...|   ||.:|           :|.:..:    .||:     ...:...||   ||.||..
plant   476 YGLTKDKTDYGWYTT-----------SFKVHKNHLPTKKGVKTFVRIASLGHALHAWLNGEYLGS 529

  Fly   532 ---------------------ENWR-----STAFPLEQSAVELWRREHTDEKALDPLLARQRILR 570
                                 ||..     .|.||...|.:|   ..:|..:.:..|
plant   530 GHGSHEEKSFVFQKQVTLKAGENHLVMLGVLTGFPDSGSYME---HRYTGPRGISIL-------- 583

  Fly   571 NGPILYTGSLTVTE-------VG--------------------------------DTY------- 589
             |  |.:|:|.:||       :|                                .||
plant   584 -G--LTSGTLDLTESSKWGNKIGMEGEKLGIHTEEGLKKVEWKKFTGKAPGLTWYQTYFDAPESV 645

  Fly   590 ----LNMAGWGKGVAYVNGFNLGRYW-----PVAGP-QVTLYVPNEILKVGENSLVILEYQRANK 644
                :.|.|.|||:.:|||..:||||     |:..| |:..::|...||..:|.|||.| :..|.
plant   646 SAATIRMHGMGKGLIWVNGEGVGRYWQSFLSPLGQPTQIEYHIPRSFLKPKKNLLVIFE-EEPNV 709

  Fly   645 TATGEDLPAVQFDAVAQLDGES 666
            .....|...|..|.|....||:
plant   710 KPELMDFAIVNRDTVCSYVGEN 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	104/350 (30%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	30/122 (25%)
BGAL11	NP_567973.1	PLN03059	41..839	CDD:166698	191/771 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820