DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL12

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001329559.1	Gene:	BGAL12 / 828720	AraportID:	AT4G26140	Length:	753	Species:	Arabidopsis thaliana

Alignment Length:	754	Identity:	184/754 - (24%)
Similarity:	292/754 - (38%)	Gaps:	209/754 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 IDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNW 112
            :.::....:::||....:|||.||.|:.||.|...::..:..||:.:.|||.|:.|.|..|:|.:
plant    29 VTYDRKAVIINGQRRILLSGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGQYYF 93

  Fly   113 EGIADVVKFLEIAQEEDFYIILRPGPYICAERDNGGLPHWLFTKY-PSIKMRTNDPNYISEVGKW 176
            |...|:|||:::.|:...|:.||.|||:|||.:.||.|.||  || |.:..||::..:.:.:.|:
plant    94 EDRYDLVKFIKVVQQAGLYVHLRIGPYVCAEWNFGGFPVWL--KYVPGMVFRTDNEPFKAAMQKF 156

  Fly   177 YAEL--MPRLQHLFVGNGGKIIMVQVENEYGDY-----ACDHDYLNWLRDETEKYVSGKALLFTV 234
            ..::  |.:.:.||...||.||:.|:|||||..     |....|..|:.:..:...:|...:...
plant   157 TEKIVRMMKEEKLFETQGGPIILSQIENEYGPIEWEIGAPGKAYTKWVAEMAQGLSTGVPWIMCK 221

  Fly   235 --DIPNEKM-SCGKIENVFATTDFGIDRINEIDKIWAMLRALQPTGPLVNSEFYPGWLTHWQEQN 296
              |.||..: :|    |.|...:|..:..|: .|:|              :|.:.||.|.:....
plant   222 QDDAPNSIINTC----NGFYCENFKPNSDNK-PKMW--------------TENWTGWFTEFGGAV 267

  Fly   297 QRRDGQEVA-NALRTILSYNASVNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDE 360
            ..|..:::| :..|.|.:..:.:|.||:.|||||..|||.         :.|  |||||||.:||
plant   268 PYRPAEDIALSVARFIQNGGSFINYYMYHGGTNFDRTAGE---------FIA--TSYDYDAPLDE 321

  Fly   361 AG--------------------------------------------------GVTTKYNLVKAVI 375
            .|                                                  ...:.||...|..
plant   322 YGLPREPKYSHLKRLHKVIKLCEPALVSADPTVTSLGDKQEAHVFKSKSSCAAFLSNYNTSSAAR 386

  Fly   376 GEF------LPLPEITLNPAKRLAY---GRVEL-TPKLTLLSTEGRAALSKGDPVESIKPK---- 426
            ..|      ||...:::.|..:..|   .:|:: |..:.:.........|.|...|.|...
plant   387 VLFGGSTYDLPPWSVSILPDCKTEYYNTAKVQVRTSSIHMKMVPTNTPFSWGSYNEEIPSANDNG 451

  Fly   427 TF------EELDLYSGLVLYETELPSMDLDP---------ALLKIDQINDRAHVFVDQELVGTLS 476
            ||      |::.:......|...|..:.:.|         .||.|.......||||:.:|.|.:
plant   452 TFSQDGLVEQISITRDKTDYFWYLTDITISPDEKFLTGEDPLLTIGSAGHALHVFVNGQLAGNI- 515

  Fly   477 REAQIY---SLPLSK---------GWGS-------------------TLQLLVENQGRVNFYISN 510
            :..|.:   |||||.         .:||                   .|.||....|..|..:..
plant   516 KIGQTHPHGSLPLSSVKHFFVSGTAYGSLEKPKLTFSQKIKLHAGVNKLALLSTAAGLPNVGVHY 580

  Fly   511 DT--KGIFGEVSLQLHNGGYLPLENWR-----------STAFPLEQSAVELWRREHTDEKALDPL 562
            :|  .|:.|.|:|...|.|...:..|:           .:...|..|:...|:.        ..|
plant   581 ETWNTGVLGPVTLNGVNSGTWDMTKWKWSYKIGTKGEALSVHTLAGSSTVEWKE--------GSL 637

  Fly   563 LARQRILRNGPILYTGSLTVTEVGD--TYLNMAGWGKGVAYVNGFNLGRYWPV------------ 613
            :|:::     |:.:..|...:..|:  ..|:|...|||..::||.|:||:||.
plant   638 VAKKQ-----PLTWYKSTFDSPTGNEPLALDMNTMGKGQMWINGQNIGRHWPAYTARGKCERCSY 697

  Fly   614 AG--------------PQVTLYVPNEILKVGENSLVILE 638
            ||              .|...:||...||...|.:::||
plant   698 AGTFTEKKCLSNCGEASQRWYHVPRSWLKPTNNLVIVLE 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	107/383 (28%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	23/94 (24%)
BGAL12	NP_001329559.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820