DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and AT2G16730

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_179264.2	Gene:	AT2G16730 / 816174	AraportID:	AT2G16730	Length:	848	Species:	Arabidopsis thaliana

Alignment Length:	812	Identity:	208/812 - (25%)
Similarity:	323/812 - (39%)	Gaps:	251/812 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LIIAVMALTVGLCVGLSGD-----TDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPE 77
            |::||:.:.:.....||.|     |.:.:::...|.|  ..:.:::|......|||.||.|:.||
plant    11 LLLAVLVILLSFSGALSSDDKEKKTKSVDKKKEVTYD--GTSLIINGNRELLYSGSIHYPRSTPE 73

  Fly    78 SWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICA 142
            .|.:.::..:..|||.:.|||.|::|.|..|::|:.|.||:|||:::.::...|:.||.||:|.|
plant    74 MWPNIIKRAKQGGLNTIQTYVFWNVHEPEQGKFNFSGRADLVKFIKLIEKNGLYVTLRLGPFIQA 138

  Fly   143 ERDNGGLPHWLFTKYPSIKMRT-NDPNYISEVGKWYAEL---MPRLQHLFVGNGGKIIMVQVENE 203
            |..:||||:|| .:.|.|..|| |:|  ..|..:.|.::   |.:.:.||...||.||:.|:|||
plant   139 EWTHGGLPYWL-REVPGIFFRTDNEP--FKEHTERYVKVVLDMMKEEKLFASQGGPIILGQIENE 200

  Fly   204 YG--DYACDHDYLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKIENVFATTDFGIDRINEIDKI 266
            |.  ..|...|.||::     |:.|                     .:..:.|.||.
plant   201 YSAVQRAYKEDGLNYI-----KWAS---------------------KLVHSMDLGIP-------- 231

  Fly   267 WAMLRALQPTGPLVNS-------EFYPG---------WLTHWQEQNQ-------RRDGQEVANAL 308
            |.|.:......|::|:       :.:||         |..:|..|.:       :|..:::|.::
plant   232 WVMCKQNDAPDPMINACNGRHCGDTFPGPNKDNKPSLWTENWTTQFRVFGDPPAQRSVEDIAYSV 296

  Fly   309 RTILSYNAS-VNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAG-GVTTKYNLV 371
            ....|.|.: ||.||:.||||||.|: |:|          ..|.|..||.:||.| ....||..:
plant   297 ARFFSKNGTHVNYYMYHGGTNFGRTS-AHY----------VTTRYYDDAPLDEFGLEREPKYGHL 350

  Fly   372 KAVIGEFLPLPEITLNPAKR-LAYG--RVELTPKLTLL------STEGRAAL---SKGDPVESIK 424
            |.:        ...||..|: |.:|  |||.....|.:      .|:..||.   :..:..|.||
plant   351 KHL--------HNALNLCKKALLWGQPRVEKPSNETEIRYYEQPGTKVCAAFLANNNTEAAEKIK 407

  Fly   425 PKTFEELDLYSGL--------VLYET-ELPSMDLDPALLKIDQIND---------------RAHV 465
            .:..|.|..:..:        |:|.| |:.|.......:|..:.|.               :...
plant   408 FRGKEYLIPHRSISILPDCKTVVYNTGEIISHHTSRNFMKSKKANKNFDFKVFTESVPSKIKGDS 472

  Fly   466 FVDQELVGTLSREAQIYSLPLSKGWGSTLQLLVENQ------GRVNFYISNDTKGIFGEVSLQLH 524
            |:..||.| |:::...|      ||.:|...:.:|.      |:.|..|::        :...||
plant   473 FIPVELYG-LTKDESDY------GWYTTSFKIDDNDLSKKKGGKPNLRIAS--------LGHALH 522

  Fly   525 ---NGGYL----------------PL-----ENWRS-----TAFPLEQSAVELWRREHTDEKALD 560
               ||.||                |:     ||..:     |.||...|.:|   ..:|..:::.
plant   523 VWLNGEYLGNGHGSHEEKSFVFQKPVTLKEGENHLTMLGVLTGFPDSGSYME---HRYTGPRSVS 584

  Fly   561 PLLARQRILRNGPILYTGSLTVTE-------VG-------------------------------- 586
                   ||..|    :|:|.:||       ||
plant   585 -------ILGLG----SGTLDLTEENKWGNKVGMEGERLGIHAEEGLKKVKWEKASGKEPGMTWY 638

  Fly   587 DTY-----------LNMAGWGKGVAYVNGFNLGRYW-----PVAGP-QVTLYVPNEILKVGENSL 634
            .||           :.|.|.|||:.:|||..:||||     |:..| |:..::|...||..:|.|
plant   639 QTYFDAPESQSAAAIRMNGMGKGLIWVNGEGVGRYWMSFLSPLGQPTQIEYHIPRSFLKPKKNLL 703

  Fly   635 VILEYQRANKTATGEDLPAVQFDAVAQLDGES 666
            ||.| :..|......|...|..|.|....||:
plant   704 VIFE-EEPNVKPELIDFVIVNRDTVCSYIGEN 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	106/352 (30%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	30/122 (25%)
AT2G16730	NP_179264.2	PLN03059	44..842	CDD:166698	201/779 (26%)
		Glyco_hydro_35	50..355	CDD:279624	106/360 (29%)
		BetaGal_dom4_5	475..558	CDD:290101	21/97 (22%)
		Gal_Lectin	762..842	CDD:280328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820