Protein Alignment Gal and Bin2a

DIOPT Version :10

• Sequence 1: NP_608978.2
• Gene: Gal / 33839
• FlyBaseID: FBgn0001089
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_001009524.2
• Gene: Bin2a / 494244
• RGDID: 1359233
• Length: 637
• Species: Rattus norvegicus
• Alignment Length: 662
• Identity: 213/662 - (32%)
• Similarity: 321/662 - (48%)
• Gaps: 98/662 - (14%)

  Fly    20 IAVMALTVGLCVGLSGDTDAPEEQPRFTIDH---------------EANTFMLDGQPFRYVSGSF 69
            |..::.|:|:...||.:     :.||....|               :.:.|.|:|.|||.:||:.
  Rat    13 ILCLSSTLGVMAFLSNN-----QLPRLNQSHLTPLWLLTRRVGLKVKDSQFTLEGFPFRIISGAI 72

  Fly    70 HYFRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIIL 134
            .|||...::||..||.|:|.|.|.|.|::.|:||.|..|.:.:....|:|.|:.:|.|...::||
  Rat    73 DYFRVPRQNWRQSLRKMQACGFNTLTTHIPWNLHEPTMGRFQFIENMDLVAFITMASETGLWVIL 137

  Fly   135 RPGPYICAERDNGGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRLQHLFVGNGGKIIMVQ 199
            .|||||..:.|.||||.||. |.|.:|:||....:...:.:::..|:||:..|....||.||.||
  Rat   138 CPGPYIGGDIDLGGLPSWLL-KDPKMKLRTTYKGFTKAMNRYFNNLIPRIAQLQYNKGGPIIAVQ 201

  Fly   200 VENEYGDYACDHDYLNWLR--------DETEKYVSGKALLFTVDIPNEKMSCGKIENVFATTDFG 256
            ||||||.|..|..|:.:::        ||         ||.|.| ....:..|.::||.||.
  Rat   202 VENEYGSYYMDKKYMEYVKTALVSRGIDE---------LLMTAD-DGVSLRKGHLQNVLATV--- 253

  Fly   257 IDRINEIDK-IWAMLRALQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTILSYNASVNL 320
              |:..|:| .:...:.:|...|::.:.:.......|....|..|.|.:...:|.|.:...|:|.
  Rat   254 --RMKNINKETYEDFKFIQGRSPILMTVYTTNSFDTWGALRQLGDPQMLMKDVREIFNLGFSLNF 316

  Fly   321 YMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAGGVTTKYNLVKAV---IGEFLPL- 381
            |||.||||||...||    ....||...:|||||.|::.|.|..|.:|...:..   :.:|.||
  Rat   317 YMFQGGTNFGLIGGA----QSAEGYTPVVTSYDYCALITENGDYTPEYQEFQRFFHSVTDFSPLT 377

  Fly   382 -PEITLNPAKRLAYGRVELTPKLTLLSTEGRAALSKGDPVESIKPKTFEELDLYS------GLVL 439
             |:.||.    .||..:.|...:||  .|....|.|  ..:|.:|.:.|:|.:..      |.:|
  Rat   378 RPKATLT----FAYQPLTLLYYMTL--WEVLPYLVK--TTKSSRPLSMEQLTVNGRSGQSFGYIL 434

  Fly   440 YETELPSMDLDPALLKIDQINDRAHVFVDQELVGTLSR---EAQIYSLPLSKGWGSTLQLLVENQ 501
            |||.:.:..|   |.....|.|||.||:|::.||.|.|   |..:|. .|:|. ..||::|||||
  Rat   435 YETTIFNGGL---LTSRGHIQDRAQVFLDKDYVGLLDRSNKELLLYK-DLTKK-TQTLRILVENQ 494

  Fly   502 GRVNF--YISNDTKGIFGEVSLQLHNGGYLPLENWRSTAFPLEQSAVELWRREHTD--EKALDPL 562
            ||:..  .::.:.||:.|::.|...     ||..::  .:.||...|.: :||...  :.|..|:
  Rat   495 GRLTSGQDMNKERKGLTGDIYLDKS-----PLRPFK--IYSLEMGNVFI-QREFPKYWKTATSPV 551

  Fly   563 LARQRILRNGPILYTGSLTVTE-VGDTYLNMAGWGKGVAYVNGFNLGRYWPVAGPQVTLYVPNEI 626
            :        ||..:...|...: ..||::.:..|||||..:||.:|||||.: |||.|::||...
  Rat   552 M--------GPAFFLSHLKAGDPPQDTFIQVKDWGKGVIAINGRSLGRYWNI-GPQETIFVPGSW 607

  Fly   627 LKVGENSLVILE 638
            |..|.|::::.|
  Rat   608 LHPGVNTIIMFE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:396048	116/333 (35%)
		BetaGal_dom4_5	<570..637	CDD:463857	26/67 (39%)
Bin2a	NP_001009524.2	AmyAc_family	57..368	CDD:476817	116/330 (35%)