Protein Alignment Gal and Glb1

DIOPT Version :10

• Sequence 1: NP_608978.2
• Gene: Gal / 33839
• FlyBaseID: FBgn0001089
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_001101662.1
• Gene: Glb1 / 316033
• RGDID: 1597145
• Length: 647
• Species: Rattus norvegicus
• Alignment Length: 662
• Identity: 266/662 - (40%)
• Similarity: 380/662 - (57%)
• Gaps: 50/662 - (7%)

  Fly    17 CLIIAVMALTVGLCVGLSGDTDA--PEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESW 79
            |:::.::||     :.|.|...:  ...|..|.:|::.:.|:.|||||||:|||.||||.....|
  Rat     7 CMLLPLLAL-----LQLLGAAHSFYNVSQRTFELDYKRDRFLKDGQPFRYISGSIHYFRIPRFYW 66

  Fly    80 RSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICAER 144
            ..||..|:.:||:|:.|||.|:.|.|..|:|::.|..||..|:::|.:....:|||||||||||.
  Rat    67 EDRLLKMKMAGLDAIQTYVPWNFHEPQPGQYDFSGDRDVEHFIQLAHQLGLLVILRPGPYICAEW 131

  Fly   145 DNGGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRLQHLFVGNGGKIIMVQVENEYGDY-A 208
            |.||||.||..| .||.:|::||:|::.|.||.|.|:|:::.|...|||.||.||||||||.| |
  Rat   132 DMGGLPAWLLEK-ESIVLRSSDPDYLAAVDKWLAVLLPKMKRLLYQNGGPIITVQVENEYGSYFA 195

  Fly   209 CDHDYLNWLRDETEKYVSGKALLFTVDIPNEK-MSCGKIENVFATTDFGIDRINEIDKIWAMLRA 272
            ||::||.:|......::....:|||.|...|| :.||.:::::||.|||  ....|.:.:.:.|.
  Rat   196 CDYNYLRFLEHRFRYHLGNDIILFTTDGAAEKLLKCGTLQDLYATVDFG--TTGNITRAFLIQRN 258

  Fly   273 LQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTILSYNASVNLYMFFGGTNFGFTAGANY 337
            .:|.|||:|||||.|||.||.:.:.:.:.:::..:|..:|:|.||||||||.|||||.:..|||
  Rat   259 FEPKGPLINSEFYTGWLDHWGQPHSKVNTKKLVASLYNLLAYGASVNLYMFIGGTNFAYWNGAN- 322

  Fly   338 NLDGGIGYAADITSYDYDAVMDEAGGVTTKYNLVKAVIGEFLPLPEITLNPA-KRLAYGRVELTP 401
                 :.||...|||||||.:.|||.:|.||..|:.||.:|..:||..:.|: .:.|||:|.|..
  Rat   323 -----MPYAPQPTSYDYDAPLSEAGDLTEKYFAVRDVIRKFKEVPEGPIPPSTPKFAYGKVALRK 382

  Fly   402 KLTLLSTEGRAALSKGDPVESIKPKTFEELDLYSGLVLYETELPSMDLDPALL---KIDQINDRA 463
            ..|:  ||....|....||:|:.|.||.::..|.|.|||.|.||....:|..:   .|:.:.|||
  Rat   383 FKTV--TEALGILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPINGVRDRA 445

  Fly   464 HVFVDQELVGTLSREAQIYSLPLSKGWGSTLQLLVENQGRVNFYIS-NDTKGIFGEVSLQLHNGG 527
            :|.||....|.|.|. ::..|.:....|:||.:||||.||||:..| .|.||:...::|     .
  Rat   446 YVSVDGVPQGILDRN-RMNVLNIRGKAGATLDILVENMGRVNYGNSIKDFKGLISNMTL-----N 504

  Fly   528 YLPLENWRSTAFPLEQSAV---ELWRREHTDEKALDPLLARQRILRNG----PILYTGSLTVTE- 584
            :..|.||  |.|||:..|:   .|...|..||..||    ....||:.    |..|.|:.::..
  Rat   505 FTVLTNW--TMFPLDTEALARSHLGNWEAADEGHLD----GHSTLRSSNFTLPTFYVGNFSIPSG 563

  Fly   585 ----VGDTYLNMAGWGKGVAYVNGFNLGRYWPVAGPQVTLYVPNEILKV-GENSLVILEYQRANK 644
                ..||::...||.||..::||||||||||..|||:||:||..||.. ..|::.:||.:.:..
  Rat   564 IPDLPQDTFIQFPGWAKGQVWINGFNLGRYWPTKGPQMTLFVPRNILTTSAPNNITVLELESSPC 628

  Fly   645 TATGEDLPAVQF 656
            :....:|..|:|
  Rat   629 SNGTLELCTVEF 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:396048	152/323 (47%)
		BetaGal_dom4_5	<570..637	CDD:463857	30/76 (39%)
Glb1	NP_001101662.1	Glyco_hydro_35	41..356	CDD:396048	152/323 (47%)
		BetaGal_dom4_5	<553..621	CDD:463857	28/67 (42%)