Protein Alignment Gal and bgal-1

DIOPT Version :9

• Sequence 1: NP_608978.2
• Gene: Gal / 33839
• FlyBaseID: FBgn0001089
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_505849.2
• Gene: bgal-1 / 188583
• WormBaseID: WBGene00011832
• Length: 653
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 251/653 - (38%)
• Similarity: 351/653 - (53%)
• Gaps: 66/653 - (10%)

  Fly    35 GDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSRLRTMRASGLNALDTYVE 99
            ||.:.|.    |.||...|.|:|||.||||:|||.||||...:.|..||..:||.|.||:..|:.
 Worm    35 GDRNIPS----FLIDESKNQFLLDGLPFRYISGSIHYFRIPRDRWDERLGKVRALGFNAIQYYIP 95

  Fly   100 WSLHNPHDGEYNWEGIADVVKFLEIA-QEEDFYIILRPGPYICAERDNGGLPHWLFTKYPSIKMR 163
            |::|...:|.:::.|:.|..:|..:| .:...:.|||.|||||.|.:|||||.||..|..: |.|
 Worm    96 WNMHELEEGNHDFSGLLDFAEFSMMAFHKYGLWTILRVGPYICGELENGGLPWWLLNKNVT-KQR 159

  Fly   164 TNDPNYISEVGKWYAELMPRLQHLFVGNGGKIIMVQVENEYGDY-ACDHDYLNWLRDETEKYVSG 227
            ::|..:..||..|:..|:||::.|...|||.::|:|:|||||.| |||..||.:|||.|...|..
 Worm   160 SSDRVFTREVENWFEILLPRVKPLLRKNGGPVLMLQIENEYGSYDACDQQYLRFLRDLTRSLVGD 224

  Fly   228 KALLFTVDIPNEK-MSCGKIENVFATTDFG-IDRINEIDKIWAMLRALQPTGPLVNSEFYPGWLT 290
            ..||||.|...|. :.||.:|.||.|.||| .|...||:..:.:.|...|.|||||||:|||||.
 Worm   225 DVLLFTTDGSAESLLKCGTVEGVFPTVDFGPTDDAKEIENNFKLQRKFAPNGPLVNSEYYPGWLV 289

  Fly   291 HWQEQNQRRDG-QEVANALRTILSYNASVNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDY 354
            .|.::.|.... |.:.|..:|:.|..||.|.||..|||||||..||...       |..||||||
 Worm   290 LWGQKKQNLPSPQTIINGSQTMYSLGASFNYYMIHGGTNFGFWNGAETE-------APCITSYDY 347

  Fly   355 DAVMDEAGGVTTKYNLVKAVIGEFL--PLPEITL---NPAKRLAYGRVEL-----TPKLTLLSTE 409
            ||.:.|:|.|||||..::..|....  |.|.:.:   :|..|  :|::::     ..||..|::.
 Worm   348 DAPISESGDVTTKYLEIRKWIKGLTDWPTPPLDVPGNSPKGR--FGKIKMRLVHSVEKLKTLTSL 410

  Fly   410 GRAALSKGDPVESIKPKTFEELDLYSGLVLYETELPSMDLDPALLKIDQINDRAHVFVDQELVGT 474
            |    ..||.||:.||.:||.|....|||.|:.::.|.    ..|.|....|..||:::.:.:.|
 Worm   411 G----DPGDCVETDKPISFETLKHPLGLVAYQAKINSC----GNLTIPSFGDFVHVYLNGKYIDT 467

  Fly   475 LSREAQIYSLPLS--------KGWGSTLQLLVENQGRVNFYISNDTKGIFGEVSLQLHNGGYLPL 531
            |:|  :.|:|..:        :...:.|.:|||||||..|...||.|||..:|.:   ||..:..
 Worm   468 LTR--RYYNLTRNSVIIEGCLENEENRLFMLVENQGRKTFETINDRKGILSDVFM---NGQAIQF 527

  Fly   532 ENWRSTAFPLEQSAVELWRREHTDEKALDPLLARQRILRNGPILYTGSLTVTEVGDTYLNMAGWG 596
            ........||::   :.:.|:.........:.:.|   :.|  ::.|.|:|....||:|:..|||
 Worm   528 WTQCGIKLPLQE---DFYFRKAMRNNYRKNVKSNQ---KQG--VFIGILSVDAPTDTWLDTTGWG 584

  Fly   597 KGVAYVNGFNLGRYWPVAGPQVTLYVPNEILKVGENSLVILEYQRANKTATGE--------DLPA 653
            ||:|.|||.|.|||||..|||:|||:|.|.||:||||::::|.:.|.:..|..        |.|.
 Worm   585 KGIAIVNGRNFGRYWPTKGPQMTLYIPAEFLKIGENSVMMVELEGAEEACTSTSSCIADFIDHPV 649

  Fly   654 VQF 656
            ..|
 Worm   650 FDF 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	147/326 (45%)
		BetaGal_dom4_5	<570..637	CDD:290101	36/66 (55%)
bgal-1	NP_505849.2	Glyco_hydro_35	50..369	CDD:279624	147/326 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162782
Domainoid	1	1.000	284	1.000	Domainoid score	I859
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	412	1.000	Inparanoid score	I1040
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52178
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	1	1.000	-	-		FOG0002046
OrthoInspector	1	1.000	-	-		mtm4799
orthoMCL	1	0.900	-	-		OOG6_100579
Panther	1	1.100	-	-	O	PTHR23421
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1174
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770