Protein Alignment Gal and bgal-2

DIOPT Version :9

• Sequence 1: NP_608978.2
• Gene: Gal / 33839
• FlyBaseID: FBgn0001089
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_509140.2
• Gene: bgal-2 / 180945
• WormBaseID: WBGene00019225
• Length: 642
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 210/672 - (31%)
• Similarity: 322/672 - (47%)
• Gaps: 96/672 - (14%)

  Fly    18 LIIAVMALTVGLCVGLSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSR 82
            |:.:|.|...|        ||:   .|.|.||...:.|:|||.||.|::|..||||...:.|..|
 Worm     9 LVCSVFATVFG--------TDS---SPSFKIDTVNSQFLLDGDPFTYIAGEIHYFRIPHQKWDDR 62

  Fly    83 LRTMRASGLNALDTYVEWSLHNPHDGEYN-WEGIADVVKFLEIAQEEDFYIILRPGPYICAERDN 146
            |:.:||.|.||:...|.|:||..:..|.. ..|..|:|||::.|:....|.|||.||||.||.||
 Worm    63 LKRVRALGFNAITVPVPWNLHQFYQDETPILSGNLDLVKFIKAAESNGLYTILRIGPYISAEWDN 127

  Fly   147 GGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRLQHLFVGNGGKIIMVQVENEYGDYA-CD 210
            ||||.||.......|.|::||::::||.:|:..|:|::..|...|.|.::|||:|:.||... ||
 Worm   128 GGLPWWLIRNTKIGKYRSSDPSFMTEVTQWWKHLLPKIYPLMRKNAGPVLMVQIEHFYGALGICD 192

  Fly   211 HDYLNWLRDETEKYVSGKALLFTVDIP-NEKMSCGKIENVFATTDFGIDRIN--EIDKIWAMLRA 272
            ..||..|.:..::.:....:||||:.| .:.|.||.:.|:..|.:. :...|  ||:..::|.:|
 Worm   193 QQYLLQLANMAKENLGNDVVLFTVNPPVLQFMRCGTLPNILPTIEI-VPNANAGEIESWFSMQKA 256

  Fly   273 LQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVAN---------ALRTILSYNASVNLYMFFGGTN 328
            .....|.|.|:|.......|        |:.|::         ..:|..:.|||::.:|..||||
 Worm   257 FMQGAPAVASQFLINPFKLW--------GKNVSDPYPNNLIIQTAKTAFALNASLSFHMTHGGTN 313

  Fly   329 FGFTAGANYNLDGGIGYAADITSYDYDAVMDEAGGVTTKY----NLVKAVIGEFLPLPEITLNPA 389
            ||:..||       :......||||..|.:.|||.|...|    |.:..:.|...|...|..| .
 Worm   314 FGYWNGA-------VDPYPVTTSYDSFAPISEAGDVNPLYISIRNWISNIPGWQNPPTPIPAN-L 370

  Fly   390 KRLAYGRVELTPKLTLLSTEGRAALSKGDPVESI--KPKTFEELDLYSGLVLYETELPSMDLDPA 452
            .|.||..|:    ||:..|.....:.......|.  .|:|.|.:....|.:.|.|.:    ::..
 Worm   371 PRTAYPDVQ----LTVFDTISGFIIGANPECWSSPETPRTAEYIRQGYGYIYYNTTI----IECG 427

  Fly   453 LLKIDQINDRAHVFVDQELVGTLSREAQIYSLPLSKGWGS----------------TLQLLVENQ 501
            .|.|....|.|::|::|..||.|.::           :||                :|::::|..
 Worm   428 SLYIPTFADNAYIFLNQNFVGALYKQ-----------FGSIHNNTIDVQGCLDQFNSLEIIIEIT 481

  Fly   502 GRVNFYISNDTKGIFGEVSLQLHNGGYLPLENWRSTAFPLEQSAVELWR-----REHTDEKALDP 561
            ||.:......::||.|.|.::     .:.||||.|...|:|...:.|.:     ::|..| .:|.
 Worm   482 GRDHNNYPVMSRGIQGNVYMR-----NITLENWESCEVPIETYEISLVKNYESLKQHVFE-TIDF 540

  Fly   562 LLARQRILRNGPILYTGSLTV-TEVGDTYLNMAGWGKGVAYVNGFNLGRYWPVAGPQVTLYVPNE 625
            ..::...:.. |.::.|:|.: |...||:|:..||||||..:|.:|:||||...|||.|||:|:|
 Worm   541 EKSQSAAIEQ-PSVFIGNLIIKTAPADTFLDTRGWGKGVVTINQYNIGRYWASIGPQQTLYIPSE 604

  Fly   626 ILKVGENSLVILEYQRANKTAT 647
            .|..|||.::..|::.|....|
 Worm   605 FLHKGENLIMFYEFEGATTACT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	118/339 (35%)
		BetaGal_dom4_5	<570..637	CDD:290101	31/67 (46%)
bgal-2	NP_509140.2	Glyco_hydro_35	34..354	CDD:366567	118/335 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162783
Domainoid	1	1.000	284	1.000	Domainoid score	I859
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	412	1.000	Inparanoid score	I1040
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52178
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4799
orthoMCL	1	0.900	-	-		OOG6_100579
Panther	1	1.100	-	-	O	PTHR23421
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1174
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.770