DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gal and LOC100332851

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_021335126.1	Gene:	LOC100332851 / 100332851	-ID:	-	Length:	633	Species:	Danio rerio

Alignment Length:	682	Identity:	220/682 - (32%)
Similarity:	333/682 - (48%)	Gaps:	97/682 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RRNRK-------LTMAVSGCLII----------AVMALTVGLCVGLSGDTDAPEEQPRFTIDHEA 52
            |:|.|       |::|   |.||          .:::.::||..                   .:
Zfish     7 RQNHKRRYVILFLSLA---CFIIYRHFRGPSGKIIISRSMGLTA-------------------NS 49

  Fly    53 NTFMLDGQPFRYVSGSFHYFRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIAD 117
            :.|.|.|:|||.:.||.||||.....||.|:..|:|.|||.:...|.||||.|...|.:::|..|
Zfish    50 SQFTLGGKPFRILGGSLHYFRLPRAYWRDRMVKMKACGLNTVTVDVPWSLHQPQKEELHFQGGLD 114

  Fly   118 VVKFLEIAQEEDFYIILRPGPYICAERDNGGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMP 182
            :..||::|.:...::||||||||..:.|.||||.||. :...:.:||..|.:|:.|..::.:|:|
Zfish   115 LEAFLQLAADVGLWVILRPGPYIGTDLDLGGLPSWLL-RDREMMLRTTYPGFIAAVNVYFDKLIP 178

  Fly   183 RLQHLFVGNGGKIIMVQVENEYGDYACDHDYLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKIE 247
            ::..|....||.||.|||||:||.:|.|.:|::::::..::....:||| |.| .:|.:..|.::
Zfish   179 KVVPLQFKKGGPIIAVQVENKYGSHARDGNYMSFIKEALQERGISEALL-TSD-NHEGLKHGGVK 241

  Fly   248 NVFATTDFGIDRINEIDKIWAMLRALQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTIL 312
            ....|.:....:.::|    ..|.|:||..|::..|.:.|....|...:.....:::.:.:|.:|
Zfish   242 GALRTLNLQKMKHDDI----KYLEAVQPNSPVLVMELWTGRCDGWGGLHHSFAAEDLVSVVREML 302

  Fly   313 SYNASVNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAGGVTTKYNLVKAVIGE 377
            ....|:|||||:|||||||..||..|    ..|.|.:|||||||.:.|||..|.||:|::.:...
Zfish   303 RRGMSINLYMFYGGTNFGFMNGALAN----PSYKALVTSYDYDAPLSEAGDYTPKYHLLRDLFSN 363

  Fly   378 FLP--LPEITLNPAKRL--AYGRVELTPKLTLLSTEGRAALSKGDPVESIKPKTFEELDLYS--- 435
            |..  |||:   |..|.  .|....|...|:|..    |.....:|..:..|...|.|.:.:
Zfish   364 FNKEILPEM---PGLRWKEQYEAAILFQHLSLWD----ALPFTHEPFRAQFPVNMESLPVNNGNG 421

  Fly   436 ---GLVLYETELPSMDLDPALLKIDQINDRAHVFVDQELVGTLSREAQIYSLPLSKGWGSTLQLL 497
               |..||||   |:....:|.....:.|||.|||:|..:|:........::|..|| ..||.||
Zfish   422 QAYGYTLYET---SITRGGSLKSGGNVQDRALVFVNQSFIGSFHHRNLELAVPDGKG-KRTLSLL 482

  Fly   498 VENQGRVNF--YISNDTKGIFGEVSLQLHNGGYLPLENWRSTAFPLEQSAV---ELWRR--EHTD 555
            |||.|||:.  .:.|..|||.|::.|     ...||.::  |.:.|:.:..   .|:|.  :...
Zfish   483 VENCGRVHSGKEMDNQRKGIVGDILL-----NRTPLRDF--TIYSLDMTPAFINSLYRANWKTVP 540

  Fly   556 EKALDPLLARQRILRNGPILYTGSLTVTEVGDTYLNMAGWGKGVAYVNGFNLGRYWPVAGPQVTL 620
            .|...|...:.|:..||   |.        .||::.:.||.|||.:|||.|:||||. ||||..|
Zfish   541 SKPSFPGFFQGRLFVNG---YP--------SDTFMKLPGWSKGVVFVNGQNIGRYWD-AGPQQAL 593

  Fly   621 YVPNEILKVGENSLVILEYQRANKTATGEDLP 652
            ::|...|..|.|.:::.|...|:.....||.|
Zfish   594 FLPGPFLNSGMNQVIVFEEAEADLKTQFEDSP 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	120/321 (37%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	27/66 (41%)
LOC100332851	XP_021335126.1	AmyAc_family	51..362	CDD:324178	120/321 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940