Protein Alignment Tsp26A and CD151

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_004348.2
• Gene: CD151 / 977
• HGNCID: 1630
• Length: 253
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 65/331 - (19%)
• Similarity: 114/331 - (34%)
• Gaps: 113/331 - (34%)

  Fly   117 SNEYTQLMCNFLEVVEMHE-EFLQTLEDCNDRVGKVF-------LSNAPTM--KKIHQFYCAAHP 171
            |..|...|.|..|:..... |.|:.|.|.|:..|::|       |.|..:|  |.|...|...|
Human   150 SKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFH- 213

  Fly   172 RAIVIVDKFRDELNVFMEKQGAAKPGLLVLTTGLSKPF---RRLDKYAAILQELERHMESGHPDR 233
             |::.......::.||      .:|          :||   ..:|....::
Human   214 -AVLKCGHLTADVQVF------PRP----------EPFVIDEEIDPIPKVI-------------- 247

  Fly   234 GDTQRSIAVYKDIASSCSATRRQKELELQILTGPVRGWQGAELSTLGDIIHMGSVAVGPEHKDRY 298
             :|...|..:.|||...|.....:.|.|.|           .|:..||.:..|   :..:::|
Human   248 -NTDLEIVGFIDIADISSPPVLSRHLVLPI-----------ALNKEGDEVGAG---ITDDNED-- 295

  Fly   299 LVLFPQTLLILSVSQRMSAFKYEGKLPLTGITVNRLEDTDQLKNAFEISGTL-IDRIVAVCQ-GP 361
                           ..||.:..||:|...:.::               |:| ::.:||:.| ||
Human   296 ---------------ENSANQIAGKIPNFCVLLH---------------GSLKVEGMVALVQLGP 330

  Fly   362 NEANRWVELLSPKSGAAEQGNTGAVDMKRNVSSSAVNIPQPPPHVSML-----MSAARAVPSEHG 421
                .|..:|..::.:.::.|.        :.|.....|:|.|.:..:     :|.|:..|  :|
Human   331 ----EWHGMLYSQADSKKKSNL--------MMSLFEPGPEPLPWLGKMAQLGPISDAKENP--YG 381

  Fly   422 KNDANS 427
            ::|..|
Human   382 EDDNKS 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	22/86 (26%)
		TM4SF9_like_LEL	118..239	CDD:239412	26/133 (20%)
CD151	NP_004348.2	Tetraspanin	16..246	CDD:459767	26/113 (23%)
		CD151_like_LEL	112..220	CDD:239408	20/71 (28%)