Protein Alignment Tsp26A and CD9

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001400170.1
• Gene: CD9 / 928
• HGNCID: 1709
• Length: 255
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 58/278 - (20%)
• Similarity: 89/278 - (32%)
• Gaps: 105/278 - (37%)

  Fly   180 FRDELNVFMEK---QGAAKP-----GLLVLTTGLSKPF-RRL---------------DKYAAILQ 220
            ||..|.:|.::   ||...|     .||...||..|.| .||               :|....|:
Human     2 FRQLLRLFRKESGDQGETTPRQKEDDLLSSKTGRRKSFWGRLGFGRKTSSQNVISEQEKCRKELE 66

  Fly   221 ELERHMESGHPDRGDTQR--SIAVYKDIASSCSATRRQKELELQILTGPVRGWQGAELSTLGDII 283
            ||:..::....:|.:..:  .:.:|.|       ...:.::||.||..
Human    67 ELKLEIQKCKFERDELYQILDLYIYDD-------WDLRLDVELPILQS----------------- 107

  Fly   284 HMGSVAVGPEHKDRYLVLFPQTLLILSVSQRMSAFKYEGKLPLTGITVNR---------LEDTDQ 339
                     ||:.|   :....::..|:|..|..:|   :|    |..|.         |.:..|
Human   108 ---------EHERR---MMSMQMMTNSISDAMERYK---EL----IQANSSYRIRHSQLLREQAQ 153

  Fly   340 LKNAFEISGTLIDRIVAVCQGPNEANRWVELLSPK-SGAAEQGNTGA--VDMKRNVSSSAVNIPQ 401
            |||..:|                       ||:.| ....||....|  |:.||....:.:||..
Human   154 LKNKIQI-----------------------LLNEKREQLVEQTELPASYVEAKRLCEEAGMNICV 195

  Fly   402 PPPHVSM-LMSAARAVPS 418
            |...... |:.|...||:
Human   196 PSAKQQQPLLPALLQVPA 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	6/16 (38%)
		TM4SF9_like_LEL	118..239	CDD:239412	20/84 (24%)
CD9	NP_001400170.1	Tetraspanin	10..246	CDD:459767	54/270 (20%)
		CD9_LEL	138..220	CDD:239405	22/99 (22%)