DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp26A and TSPAN4

DIOPT Version :10

Sequence 1:NP_001097093.1 Gene:Tsp26A / 33838 FlyBaseID:FBgn0031760 Length:314 Species:Drosophila melanogaster
Sequence 2:NP_001426622.1 Gene:TSPAN4 / 7106 HGNCID:11859 Length:330 Species:Homo sapiens


Alignment Length:300 Identity:81/300 - (27%)
Similarity:122/300 - (40%) Gaps:78/300 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 CL---KYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAFVLIILGGVTFLLG 79
            ||   |||:||.|::.||....||.||||..:.:|.|..::. .|.:|..|.:|||.|.....:|
Human    97 CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS-SFPSLSAANLLIITGAFVMAIG 160

  Fly    80 FMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDAD 144
            |:|.:||::||.|||..:.:.|.::.:.|.....:.|...||  |...|.:.||..:..|....:
Human   161 FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDK--IDRYAQQDLKKGLHLYGTQGN 223

  Fly   145 QQNLIDW--IQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQC 207
            ......|  ||.|: :|||:....||  ...:|          |..||.|||      :..::.|
Human   224 VGLTNAWSIIQTDF-RCCGVSNYTDW--FEVYN----------ATRVPDSCC------LEFSESC 269

  Fly   208 GYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAGEE 272
            |                   |.|...|.:|                           .|.:..:.
Human   270 G-------------------LHAPGTWWKA---------------------------PCYETVKV 288

  Fly   273 WMEHNLIIISATVIVVMFFQILGICFA-----QNLRADIY 307
            |::.||:.:....:.....||||:.||     |.::||.|
Human   289 WLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTY 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp26ANP_001097093.1 Tetraspanin 19..194 CDD:459767 58/179 (32%)
TM4SF9_like_LEL 118..239 CDD:239412 29/122 (24%)
TSPAN4NP_001426622.1 None

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