Protein Alignment Tsp26A and TSPAN6

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 59/207 - (28%)
• Similarity: 98/207 - (47%)
• Gaps: 24/207 - (11%)

  Fly     9 RRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRN-IARLHFIALDPAFVLIILG 72
            |.:|..:..|.|.:|.....|.|::.:::|:||||.   |....| .:.|:..|.:..||||..|
Human     7 RLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKATNVPFVLIATG 68

  Fly    73 GVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIR 137
            .|..|||..|.....|.:..:|..||:||:::.:.|:....|.||.:.:  ||:......:..::
Human    69 TVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE--IKNSFKNNYEKALK 131

  Fly   138 HYREDAD-QQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCR------ 195
            .|....| :.:.:|.|| :.|.|||:...:||...||::          ..|.|.|||:
Human   132 QYNSTGDYRSHAVDKIQ-NTLHCCGVTDYRDWTDTNYYS----------EKGFPKSCCKLEDCTP 185

  Fly   196 RRPQEVIKNKQC 207
            :|..:.:.|:.|
Human   186 QRDADKVNNEGC 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	51/176 (29%)
		TM4SF9_like_LEL	118..239	CDD:239412	23/97 (24%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	56/197 (28%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	25/99 (25%)