Protein Alignment Tsp26A and ROM1

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_000318.2
• Gene: ROM1 / 6094
• HGNCID: 10254
• Length: 351
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 75/295 - (25%)
• Similarity: 114/295 - (38%)
• Gaps: 62/295 - (21%)

  Fly    30 LW-LSALLVLSVGIWAWSEKGMFRNIARL-HFIALDPAF-----VLIILGGVTFLLGFMGSVGAL 87
            || ||.||.|:.|:.......:...:..| .|:|....|     ..:..|.|....|.:| |||.
Human    21 LWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVG-VGAS 84

  Fly    88 RE--NTCLLGAYAIFLSVLLIAEI----GFCAV--AFVLKDKGWIKDQATEGLKAFIRHYRE--- 141
            |.  |..|...:...|..||:|..    |...|  ...|...|.:.:...|||...:.||::
Human    85 RASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVGLGLALALPGSLDEALEEGLVTALAHYKDTEV 149

  Fly   142 --DADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREAC--------------GVP 190
              ....:.|:|.:|..: .|||..|.|||....:.:...:..|.|:..              |||
Human   150 PGHCQAKRLVDELQLRY-HCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVP 213

  Fly   191 FSCCR-RRPQEVIKNKQCG------YDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVA--IG- 245
            ||||. ..|:..::|:...      :|.|:.    ::|:..:||    .:.|..||..:|  :|
Human   214 FSCCNPHSPRPCLQNRLSDSYAHPLFDPRQP----NQNLWAQGC----HEVLLEHLQDLAGTLGS 270

  Fly   246 ------CVALLVLQGMELSKIIYE--KGCVQAGEE 272
                  .:..|||.|:...:...|  .|.:.||.|
Human   271 MLAVTFLLQALVLLGLRYLQTALEGLGGVIDAGGE 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	52/197 (26%)
		TM4SF9_like_LEL	118..239	CDD:239412	34/146 (23%)
ROM1	NP_000318.2	peripherin_like_LEL	126..265	CDD:239415	35/147 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..351