Protein Alignment Tsp26A and Tspan6

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_062630.2
• Gene: Tspan6 / 56496
• MGIID: 1926264
• Length: 245
• Species: Mus musculus
• Alignment Length: 253
• Identity: 70/253 - (27%)
• Similarity: 110/253 - (43%)
• Gaps: 45/253 - (17%)

  Fly     9 RRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRN-IARLHFIALDPAFVLIILG 72
            |.:|..:..|||.:|.....|.|::.:::|:||||.   |....| .:.|:..|.:..||||..|
Mouse     7 RLQTKPVITCLKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKATNVPFVLIGTG 68

  Fly    73 GVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIR 137
            .|..|||..|.....|.:..:|..||:||:::.:.|:....|.||.:.:  ||:......:..::
Mouse    69 TVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHE--IKNSFKSNYENALK 131

  Fly   138 HYREDAD-QQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEV 201
            .|....| :...:|.||.. |.|||:....||...||::          ..|.|.|||
Mouse   132 EYNSTGDYRSEAVDKIQST-LHCCGVTNYGDWKGTNYYS----------ETGFPKSCC------- 178

  Fly   202 IKNKQCGYDVRKEG-YP---VDRNIHERGCLRAGEDWLEAHL-----ISVAIGCVALL 250
                      :.|| ||   .|: ::|.||.......:|:.:     ||..:.|..|:
Mouse   179 ----------KLEGCYPQRDADK-VNEEGCFIKVMTTIESEMGVVAGISFGVACFQLI 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	52/176 (30%)
		TM4SF9_like_LEL	118..239	CDD:239412	29/125 (23%)
Tspan6	NP_062630.2	Tetraspanin	17..235	CDD:459767	67/243 (28%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	31/127 (24%)