DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp26A and tspan14

DIOPT Version :9

Sequence 1:	NP_001097093.1	Gene:	Tsp26A / 33838	FlyBaseID:	FBgn0031760	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001007871.1	Gene:	tspan14 / 493257	XenbaseID:	XB-GENE-868280	Length:	270	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	119/307 - (38%)
Similarity:	170/307 - (55%)	Gaps:	47/307 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FRRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNI---ARLHFIALDPAFVLI 69
            :|..|:|:|||.|||||:.|:|.|||.:::|.||:|||||||:..:|   .|||  ..||.::::
Frog     4 YRYSTAEVSCCYKYLLFSYNIIFWLSGMVLLGVGLWAWSEKGILSDITKVTRLH--GFDPVWLVL 66

  Fly    70 ILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKA 134
            ::|.:.|.|||.|.|||||||.|||..:...:.::...|:....:||:.:|  |:||:|.:..:.
Frog    67 VVGVIMFTLGFAGCVGALRENICLLKFFCGAIVLIFFMELAVAVLAFLFQD--WVKDRAKDFFEN 129

  Fly   135 FIRHYREDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQ 199
            .|:.||:|.|.|||||.:|:. .||||...|.|||.|.|||| |:...|||.||||||||...|.
Frog   130 NIKSYRDDIDLQNLIDSLQKA-NQCCGAVSPDDWDLNEYFNC-SVENPSRERCGVPFSCCVPDPA 192

  Fly   200 EVIKNKQCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEK 264
            :.:.|.|||||.|::                                      :..|.....:.|
Frog   193 QTVVNTQCGYDARRK--------------------------------------KPNERPNTTFSK 219

  Fly   265 GCVQAGEEWMEHNLIIISATVIVVMFFQILGICFAQNLRADIYTQKS 311
            ||:.|.|.|:..|:.|::...:|:...||.||..|:.|.:||...|:
Frog   220 GCISALEAWLPRNIYIVAGVFLVISILQIFGIYLARTLMSDIEAVKA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspannin	18..253	CDD:278750	95/237 (40%)
		DUF2207	<65..157	CDD:303056	35/91 (38%)
		TM4SF9_like_LEL	118..239	CDD:239412	49/120 (41%)
tspan14	NP_001007871.1	TM4SF9_like_LEL	113..233	CDD:239412	57/161 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2744
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3308
OMA	1	1.010	-	-		QHG48585
OrthoDB	1	1.010	-	-		D1180379at2759
OrthoFinder	1	1.000	-	-		FOG0001766
OrthoInspector	1	1.000	-	-		otm49136
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080