Protein Alignment Tsp26A and CD82

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 86/310 - (27%)
• Similarity: 145/310 - (46%)
• Gaps: 57/310 - (18%)

  Fly    16 SCCL---KYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALD-PAFVLIILGGVTF 76
            |.|:   ||.||..|:|.::...::|..|:|..::|..|.::.:....:|. .|:|.|.:|.||.
Human    44 SACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTM 108

  Fly    77 LLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHY-- 139
            |:||:|.:||:.|..||||.|..||.::|||::  .|.|....:.|.:|.:....:...||.|
Human   109 LMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQV--TAGALFYFNMGKLKQEMGGIVTELIRDYNS 171

  Fly   140 -REDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIA-IGSREACGVPFSCCRRRPQEVI 202
             |||: .|:..|::|.. ::|||      |.|  ::|.:..| :.:|.....|.||      ||.
Human   172 SREDS-LQDAWDYVQAQ-VKCCG------WVS--FYNWTDNAELMNRPEVTYPCSC------EVK 220

  Fly   203 KNKQCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCV 267
            ..:.....|||.......|..:.|  ...|||                         .:|::||:
Human   221 GEEDNSLSVRKGFCEAPGNRTQSG--NHPEDW-------------------------PVYQEGCM 258

  Fly   268 QAGEEWMEHNLIIISATVIVVMFFQILG----ICFAQNLRADIYTQKSKW 313
            :..:.|::.||.||....:.|...::||    ||..:::.::.|::..|:
Human   259 EKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	58/182 (32%)
		TM4SF9_like_LEL	118..239	CDD:239412	32/124 (26%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	76/274 (28%)
		CD37_CD82_like_LEL	147..270	CDD:239413	37/165 (22%)