Protein Alignment Tsp26A and cd63

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_955837.1
• Gene: cd63 / 321461
• ZFINID: ZDB-GENE-030131-180
• Length: 237
• Species: Danio rerio
• Alignment Length: 282
• Identity: 78/282 - (27%)
• Similarity: 120/282 - (42%)
• Gaps: 67/282 - (23%)

  Fly    18 CLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAFVLIILGGVTFLLGFMG 82
            |:|||||..|.|.||..|.::.:||.....   ..|.|.|...:..| .|||::|.:.|.:.|.|
Zfish     9 CVKYLLFFFNFIFWLCGLALIVLGILVHVS---LHNTAILQGASGSP-MVLIVVGVIIFFISFFG 69

  Fly    83 SVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDADQQN 147
            ..||.:||.|::..:||.||:::|.|||.....::.:.|  :.:...:.....|..|.:..:.:.
Zfish    70 CCGAWKENQCMVVTFAIILSLIVITEIGAGIAGYIFRGK--VNELLDQSFNTMIAGYNKTEEYRT 132

  Fly   148 LIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQCGYDVR 212
            .:|.||:. |:|||.:...||.:   |:...|:        ||.|||:    .|.||  ||
Zfish   133 TLDSIQKQ-LKCCGGNSSSDWVN---FSADHIS--------VPDSCCK----NVTKN--CG---- 175

  Fly   213 KEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAGEEWMEHN 277
                                           ||        .|....:||.:||....|..::.|
Zfish   176 -------------------------------IG--------AMTKPTVIYLEGCQPILETRIKEN 201

  Fly   278 LIIISATVIVVMFFQILGICFA 299
            ::.|:...:|:.|.||.||..|
Zfish   202 ILWIAVGALVIGFVQITGIVLA 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	53/174 (30%)
		TM4SF9_like_LEL	118..239	CDD:239412	24/120 (20%)
cd63	NP_955837.1	Tetraspanin	10..228	CDD:459767	77/281 (27%)
		CD63_LEL	103..202	CDD:239419	32/161 (20%)