DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp26A and tsp-2

DIOPT Version :9

Sequence 1:	NP_001097093.1	Gene:	Tsp26A / 33838	FlyBaseID:	FBgn0031760	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_498803.1	Gene:	tsp-2 / 259752	WormBaseID:	WBGene00006628	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	42/193 - (21%)
Similarity:	75/193 - (38%)	Gaps:	49/193 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TSEISCCLKYLLFASNVILWLSALLVLSVGIWAW----SEKGMFRNIARLHF-------IALD-- 63
            ||.|:...:..:|..::     |:|..|:|:..|    .:|...|::..:.|       :|.|
Worm     2 TSRIAFISRITIFCLSL-----AMLFCSIGLDIWGSLMEDKSYERDLKDVVFNYNSSQPLADDKF 61

  Fly    64 -----------PAFVLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFV 117
                       ..:.|.|:.|.   |..:|.:||:.:...:|....:.:.:..|.|:| .::|.
Worm    62 DMRSWIYSVYWSIYGLCIIAGP---LSIIGLIGAISQKKPVLATCLVLIVIFFIMELG-GSIAL- 121

  Fly   118 LKDKGWIKDQATEGLKAFIRHYREDADQQNL---IDWIQEDWLQCCGI-DGPKDWDSNNYFNC 176
                 |.|   ...|::.:..:..|....|.   |..||..: .|||: ||  .|...|..:|
Worm   122 -----WSK---RGSLRSLLYRFANDIYLTNSVFDISIIQNTY-NCCGVQDG--QWKCPNAPSC 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspannin	18..253	CDD:278750	39/187 (21%)
		DUF2207	<65..157	CDD:303056	20/94 (21%)
		TM4SF9_like_LEL	118..239	CDD:239412	16/63 (25%)
tsp-2	NP_498803.1	Tetraspannin	<84..203	CDD:278750	25/103 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900