Protein Alignment Tsp26A and TSPAN15

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 89/298 - (29%)
• Similarity: 144/298 - (48%)
• Gaps: 61/298 - (20%)

  Fly     9 RRETSEISCC-------LKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAF 66
            |.::.::..|       ||:.|...:.:.||...|||||||:|..|:..::.:... |:|  ||.
Human     3 RGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESA-FLA--PAI 64

  Fly    67 VLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEI--GFCAVAFVLKDKGWIKDQAT 129
            :||:||.|.|::.|:|.:.:||:|..||.|:...|.:.||.|:  |..|:.|..:...::.|...
Human    65 ILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIR 129

  Fly   130 EGLKAFIRHYREDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCC 194
            .|    |.:|.:|.|.:|::|::|:.: :|||.:..:||..|.|.:||  |.|.. |||||::||
Human   130 RG----IENYYDDLDFKNIMDFVQKKF-KCCGGEDYRDWSKNQYHDCS--APGPL-ACGVPYTCC 186

  Fly   195 RRRPQEVIKNKQCGY-DVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELS 258
            .|...||: |..||| .:.||.:.|                                       .
Human   187 IRNTTEVV-NTMCGYKTIDKERFSV---------------------------------------Q 211

  Fly   259 KIIYEKGCVQAGEEWMEHNLIIISATVIVVMFFQILGI 296
            .:||.:||..|...|...|..|::..::.::..|.||:
Human   212 DVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	64/176 (36%)
		TM4SF9_like_LEL	118..239	CDD:239412	37/121 (31%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	50/144 (35%)
		penumbra_like_LEL	114..231	CDD:239411	44/164 (27%)