Protein Alignment Tsp26A and Tspan33

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_666285.1
• Gene: Tspan33 / 232670
• MGIID: 1919012
• Length: 283
• Species: Mus musculus
• Alignment Length: 325
• Identity: 101/325 - (31%)
• Similarity: 166/325 - (51%)
• Gaps: 59/325 - (18%)

  Fly     1 MPAAVRKFRRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPA 65
            :|||   :..|.|.:|..:|||||..|::.|:.::::::||::|   :.|....|.|..:|:|||
Mouse     7 VPAA---YGDEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYA---RLMKHAEAALACLAVDPA 65

  Fly    66 FVLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATE 130
            .:||::|.:.|||.|.|.:|:||||.|||..:::.|:::.:.::....:.||..||.  :.:.:|
Mouse    66 ILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKA--RGKVSE 128

  Fly   131 GLKAFIRHYREDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCR 195
            .:...|.|||:|.|.|||||:.|:.: .|||....:||..|.|||||. ...|||.|.||:|||.
Mouse   129 IINNAIVHYRDDLDLQNLIDFGQKKF-SCCGGISYRDWSQNMYFNCSE-DNPSRERCSVPYSCCL 191

  Fly   196 RRPQEVIKNKQCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKI 260
            ..|.:.:.|..||..::                  ..|:|||                    ||:
Mouse   192 PTPNQAVINTMCGQGMQ------------------ALDYLEA--------------------SKV 218

  Fly   261 IYEKGCVQAGEEWMEHNLIIISATVIVVMFFQILGICFAQ--------NLRADIYTQKSK---WH 314
            ||..||:.....|:..||.::....:.:...|::||..:|        .::..:|.|:.:   |:
Mouse   219 IYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQHRADPWY 283

  Fly   315  314
            Mouse   284  283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	69/174 (40%)
		TM4SF9_like_LEL	118..239	CDD:239412	43/120 (36%)
Tspan33	NP_666285.1	Tetraspanin	22..262	CDD:459767	92/284 (32%)
		penumbra_like_LEL	116..236	CDD:239411	52/161 (32%)