Protein Alignment Tsp26A and tsp-17

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001129920.2
• Gene: tsp-17 / 192067
• WormBaseID: WBGene00006643
• Length: 312
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 68/308 - (22%)
• Similarity: 117/308 - (37%)
• Gaps: 77/308 - (25%)

  Fly    18 CLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDP-----AFVLIILGGVTFL 77
            ||:..:...::..|||||..:.:|:|...:......:..:||...||     |:|.::.|....|
 Worm    10 CLRVAVSIFSIYYWLSALGHVFLGLWMLLDPKRNYILDLVHFSENDPLLKASAYVSLVCGCAQLL 74

  Fly    78 LGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDK--------------------- 121
            :||:|..||:..:..||.|:.:||....:|::....::...|||
 Worm    75 VGFLGLCGAVNRSRFLLLAFVMFLIGTFLADVAMGTLSLFYKDKFSNNYMGVYLKNLTYNRYSRD 139

  Fly   122 GW--------------IKDQATEGLKAFIRHYREDADQQNLIDWIQEDWLQ----CCGIDGPKDW 168
            .|              :|:...|.:|:.......:.:.:.:.::|  |.||    |||..||.|:
 Worm   140 RWVLPLMDTIQFYVYSVKENVREIVKSKYGVMTSEPENKMVTEFI--DKLQFYEKCCGSLGPTDY 202

  Fly   169 DSNNYFNCSSIAIGSREACGVPFSCCRR---------------RPQEVIKNKQCGYDVRKEGYPV 218
            .|:.:...::......|:...|.|||.:               |.|::..|:|..
 Worm   203 ISSRWSQSTNQDSEEIESPLFPVSCCTQITGASALNPLAKSYARCQQIGANRQWR---------- 257

  Fly   219 DRNIHERGCLRAGEDWLEAHL-ISVAIGC-VALLVLQGMELSKIIYEK 264
                |..||......|....: |.|..|. .||.::.|:.||..:..|
 Worm   258 ----HAVGCSERLMSWFNEQIWIFVGFGFGSALTMMLGICLSCCLISK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	48/218 (22%)
		TM4SF9_like_LEL	118..239	CDD:239412	31/174 (18%)
tsp-17	NP_001129920.2	Tetraspanin	11..>150	CDD:459767	31/138 (22%)
		CD37_CD82_like_LEL	153..275	CDD:239413	27/137 (20%)