Protein Alignment Tsp26A and tsp-15

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_492404.1
• Gene: tsp-15 / 192065
• WormBaseID: WBGene00006641
• Length: 258
• Species: Caenorhabditis elegans
• Alignment Length: 276
• Identity: 57/276 - (20%)
• Similarity: 110/276 - (39%)
• Gaps: 68/276 - (24%)

  Fly    19 LKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAFVLIILGGVTFLLGFMGS 83
            :|:....:.:|..|.::..:..|||..:.:..:..:.. ..:.:|...:|:|:..::.|...:..
 Worm    16 IKFSYIVTALISILFSISCICYGIWLLARRSQYAELVS-PSLYVDVGRILVIISILSILNYLICF 79

  Fly    84 VGALRENTCLLGAYA---IFLSVLLIAEIGFC-AVAFVLKDKGWIKDQATE----GLKAF--IRH 138
            ....:|..|.:.:.|   |.::|:||  ||.| .:.|        :||.|.    .||..  :|.
 Worm    80 YAIFKEMRCFVTSCAVASIVIAVMLI--IGGCIGLNF--------RDQLTHYTPLNLKMLTSLRE 134

  Fly   139 YREDADQQNLIDWIQEDW------LQCCGIDGPKD---WDSNNYF---NCSSIAIGSREACGVPF 191
            .....|.:.    |.|.|      .:|||::|..:   |.::.::   ....:.|        |.
 Worm   135 LYGTHDMKG----ITESWDALQSNFKCCGVNGTDNAQIWKTSKWYMHQRAPKLLI--------PE 187

  Fly   192 SCCRRRPQEVIKNKQCGYDVRKEGYPVDRN----IHERGCLRAGEDWLEAHLISVAIG-CVALLV 251
            |||  .|.|:   ::|      ...|.|::    .:...|....::.| .|:::||.. |:...:
 Worm   188 SCC--IPSEI---ERC------RSNPFDQDAPPPYYTSTCYEPLQNDL-LHVMNVASWLCITNAI 240

  Fly   252 LQ------GMELSKII 261
            :|      |...||:|
 Worm   241 VQIIPSVAGCWYSKLI 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	39/196 (20%)
		TM4SF9_like_LEL	118..239	CDD:239412	27/142 (19%)
tsp-15	NP_492404.1	Tetraspanin	16..>159	CDD:459767	32/157 (20%)
		uroplakin_I_like_LEL	110..228	CDD:239409	29/149 (19%)