Protein Alignment Tsp26A and TSPAN19

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 66/307 - (21%)
• Similarity: 110/307 - (35%)
• Gaps: 85/307 - (27%)

  Fly    19 LKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNI--ARLHFIALDPAFVLIILGGVTFLLGFM 81
            :||.|...|....:..||.:..|.|...::..|...  ...||| :..:.:||.:|..|.|...:
Human    10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFI-VPISQILIGMGSSTVLFCLL 73

  Fly    82 GSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHY-----RE 141
            |.:|...|...||..||:.::.....::  ...||::..|..::....:.:...|..|     .|
Human    74 GYIGIHNEIRWLLIVYAVLITWTFAVQV--VLSAFIITKKEEVQQLWHDKIDFVISEYGSKDKPE 136

  Fly   142 DADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACG-VPFSCCRRRPQEVIKNK 205
            |..:..:::.:|:. |||||.....||..|.          ::|..| ||.||.:.
Human   137 DITKWTILNALQKT-LQCCGQHNYTDWIKNK----------NKENSGQVPCSCTKS--------- 181

  Fly   206 QCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAG 270
                .:||                    |.          |        .|.....|.:||....
Human   182 ----TLRK--------------------WF----------C--------DEPLNATYLEGCENKI 204

  Fly   271 EEWMEHNLIIISATVIVVMF-------FQI-LGICFAQNLRADIYTQ 309
            ..|...|::    |:|.:.|       ||: |.:||.:|::..|:.:
Human   205 SAWYNVNVL----TLIGINFGLLTSEVFQVSLTVCFFKNIKNIIHAE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	45/182 (25%)
		TM4SF9_like_LEL	118..239	CDD:239412	23/126 (18%)
TSPAN19	NP_001094387.1	Tetraspanin	10..>155	CDD:459767	35/148 (24%)
		CD37_CD82_like_LEL	107..212	CDD:239413	29/166 (17%)