Protein Alignment Tsp26A and UPK1A

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 60/273 - (21%)
• Similarity: 105/273 - (38%)
• Gaps: 38/273 - (13%)

  Fly    22 LLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAF----VLIILGGVTFLLGFMG 82
            ||...|:|:.||.|.:.:..||..:::  :|....:.....|..|    :.|..|...|::...|
Human    20 LLVVGNIIILLSGLSLFAETIWVTADQ--YRVYPLMGVSGKDDVFAGAWIAIFCGFSFFMVASFG 82

  Fly    83 SVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDADQ-Q 146
            ...||.....::..|.:.:.::.|.|...|..::..:|  ::....:...|..:..|..|.|| |
Human    83 VGAALCRRRSMVLTYLVLMLIVYIFECASCITSYTHRD--YMVSNPSLITKQMLTFYSADTDQGQ 145

  Fly   147 NLID-W----IQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQ 206
            .|.. |    |::   :|||..||.||.:   |..:..|.........|..||||....:..|::
Human   146 ELTRLWDRVMIEQ---ECCGTSGPMDWVN---FTSAFRAATPEVVFPWPPLCCRRTGNFIPLNEE 204

  Fly   207 CGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVA-IGCVALLVLQGMELSKIIY-------E 263
             |..:....|     :..:||.......::::...:: .|...|:..:|    |..|       .
Human   205 -GCRLGHMDY-----LFTKGCFEHIGHAIDSYTWGISWFGFAILMWTEG----KATYTPRTPPHP 259

  Fly   264 KGCVQAGEEWMEH 276
            .....||..|:.|
Human   260 PPASSAGPGWLPH 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	42/181 (23%)
		TM4SF9_like_LEL	118..239	CDD:239412	29/126 (23%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	32/144 (22%)
		uroplakin_I_like_LEL	113..231	CDD:239409	29/131 (22%)