Protein Alignment Tsp26A and Upk1a

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_081091.1
• Gene: Upk1a / 109637
• MGIID: 98911
• Length: 257
• Species: Mus musculus
• Alignment Length: 290
• Identity: 60/290 - (20%)
• Similarity: 103/290 - (35%)
• Gaps: 74/290 - (25%)

  Fly    22 LLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIALDPAF----VLIILGGVTFLLGFMG 82
            ||...|:|:.||.|.:.:..:|..:::  :|....:.....|..|    :.|..|...|::...|
Mouse    18 LLVVGNIIILLSGLALFAETVWVTADQ--YRVYPLMGVSGKDDVFAGAWIAIFCGFSFFVVASFG 80

  Fly    83 SVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDADQ-- 145
            ...||.....::..|.:.:.::.|.|...|..::..:|  ::....:...|..:.:|..|.||
Mouse    81 VGAALCRRRYMILTYLLLMLIVYIFECASCITSYTHRD--YMVSNPSLITKQMLTYYSADTDQGQ 143

  Fly   146 --QNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREAC-GVPFSCCRRRPQEVIKNKQC 207
              ..|.|.|..: .:|||..||.||  .||  .|:....:.|.. ..|..||||....:
Mouse   144 ELTRLWDRIMIE-QECCGTSGPMDW--VNY--TSAFRAATPEVVFPWPPLCCRRTGNFI------ 197

  Fly   208 GYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQA--- 269
                         .|:|.||.....|:|                          :.|||.:.
Mouse   198 -------------PINEDGCRVGHMDYL--------------------------FTKGCFEHIGH 223

  Fly   270 -------GEEWMEHNLIIISATV-IVVMFF 291
                   |..|....:::.:..| ::.|:|
Mouse   224 AIDSYTWGISWFGFAILMWTLPVMLIAMYF 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	42/180 (23%)
		TM4SF9_like_LEL	118..239	CDD:239412	31/125 (25%)
Upk1a	NP_081091.1	Tetraspanin	23..>161	CDD:459767	30/142 (21%)
		uroplakin_I_like_LEL	111..229	CDD:239409	34/169 (20%)