Protein Alignment Tsp26A and TSPAN5

DIOPT Version :10

• Sequence 1: NP_001097093.1
• Gene: Tsp26A / 33838
• FlyBaseID: FBgn0031760
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 126/301 - (41%)
• Similarity: 172/301 - (57%)
• Gaps: 43/301 - (14%)

  Fly    14 EISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFI-ALDPAFVLIILGGVTFL 77
            |:|||:||.:|..|||.|...:..|.:|:|||:|||:..||:.:..: ..||.::.:::|||.|:
Human    10 EVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFI 74

  Fly    78 LGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYRED 142
            |||.|.:|||||||.||..:::||.::...|:....:|||.||  |||||....:...||.||:|
Human    75 LGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDD 137

  Fly   143 ADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQC 207
            .|.|||||:.||.| ||||..|..||:.|.||||:. :..|||.||||||||.:.|.|.:.|.||
Human   138 IDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTD-SNASRERCGVPFSCCTKDPAEDVINTQC 200

  Fly   208 GYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAGEE 272
            |||.|::. .||:.|                                     :||.||||...|:
Human   201 GYDARQKP-EVDQQI-------------------------------------VIYTKGCVPQFEK 227

  Fly   273 WMEHNLIIISATVIVVMFFQILGICFAQNLRADIYTQKSKW 313
            |::.||.|::...|.:...||.|||.||||.:||...::.|
Human   228 WLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp26A	NP_001097093.1	Tetraspanin	19..194	CDD:459767	84/175 (48%)
		TM4SF9_like_LEL	118..239	CDD:239412	56/120 (47%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	118/284 (42%)
		TM4SF9_like_LEL	113..233	CDD:239412	66/161 (41%)