Protein Alignment lid and kdm4b

DIOPT Version :9

• Sequence 1: NP_001245908.1
• Gene: lid / 33837
• FlyBaseID: FBgn0031759
• Length: 1838
• Species: Drosophila melanogaster
• Sequence 2: NP_001076274.1
• Gene: kdm4b / 556504
• ZFINID: ZDB-GENE-060503-664
• Length: 1134
• Species: Danio rerio
• Alignment Length: 1117
• Identity: 221/1117 - (19%)
• Similarity: 339/1117 - (30%)
• Gaps: 426/1117 - (38%)

  Fly   309 HPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSK------ 367
            :|.|...|..|..|..|...|...|  |.|....|....:: ..:..||...|..:..|
Zfish    10 NPAETEPSADVTPPADTDQDSPINP--LVDPQPCDTPISDL-VHEPAAPAEPTPAQGLKPELPAP 71

  Fly   368 RFGNSNASCGLSGVTPTTKPSAG---VFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRG 429
            .....|.   :.|..|...|.|.   :.....|.||||           ..|..:|   ...|:|
Zfish    72 ELTTQNL---IPGPAPAPPPGANFNKIMTFRPTMEEFK-----------DFGKYIA---YMETQG 119

  Fly   430 ASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPR 494
            |                     |:.....|                         ||..||...|
Zfish   120 A---------------------HVAGLAKV-------------------------IPPKEWKPRR 138

  Fly   495 C--VVEEVSKP----QEAFGFEQAEREYTLQQFGQMADQFKQ----EYFRKPVHLVPTEMVEREF 549
            .  .:|::..|    |...|......:|.:|:......::::    :.:..|.| ...:.:||::
Zfish   139 SYETIEDMVIPAPIMQVVTGQSGLFTQYNIQKKSMTVGEYRKLANSKKYNTPQH-KDFDDLERKY 202

  Fly   550 WR---IVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYLLPGDQEYAESSWNLNNLPLLEDSILG 611
            |:   .||.|       ||||:      ||     |||    |.:.:|  ||:.:|..|.|.:..
Zfish   203 WKNLTFVSPI-------YGADI------SG-----SLY----DPDISE--WNIGHLNTLLDMVEQ 243

  Fly   612 HINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAA 676
            .....|.|:|.|::|.||....|.||.||...|||||||:|:||:||.:|....::.|...:...
Zfish   244 ECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGKPKSWYAIPPEHGKRLERLAQGFF 308

  Fly   677 PELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFA 741
            |.........|...:|:::|:||....:|..|..|..|||:||||..||||||.|:|.||:.|||
Zfish   309 PGSSQGCDAFLRHKMTLISPSILKKYSIPFDRITQEEGEFMITFPYGYHAGFNHGFNCAESTNFA 373

  Fly   742 PADWL---KMGRECVNHYSMLRRFCVFSHDELVCKMALEPAKLTFGIATACYIDMAEMVDTEKKL 803
            ...|:   ||..:|.....|::    .|.|..|.:  |:|.:.|
Zfish   374 TLRWIDYGKMAAQCTCRKDMVK----ISMDVFVRR--LQPERYT--------------------- 411

  Fly   804 RKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACECNDKLIVCLRHYTVLCGCAPEKH 868
                 :|                                                     ...|.
Zfish   412 -----QW-----------------------------------------------------KQGKD 418

  Fly   869 TLIYRYTLDEMPLMLQKLKVKAHSFERWLSRCRDIVDAHTPTSVTLQELQELCKEAETKKF---- 929
            |::    ||.    |:...:.:...|.|           ....||.:|......:|:.|:|
Zfish   419 TMV----LDH----LKPTSLSSPELEHW-----------RKNRVTFREKVLRRAQAKMKQFRRLK 464

  Fly   930 PSSLLIDRLNAAAVEAEKCVTVIQQLGINKVRTRSDHNQEAAQYKLTMEELELFVQEIDNLCCII 994
            |..|                .|:.:.|:                :|.|||.:..|:|.|
Zfish   465 PEDL----------------KVLMEAGV----------------ELDMEEYQRKVEEHD------ 491

  Fly   995 DEGASVRELLVLGKQFVERSESQLQLSLESLEESELETLINEGSSLRIELQQLDLLQKRLKQCKW 1059
            ::....|:         ||...:..|:||:||..|.|                        |.:.
Zfish   492 EQRRQQRD---------ERMAREAMLTLEALEREEQE------------------------QAEA 523

  Fly  1060 YKRSQGLRETSSKLTYQDVKNLLHIAAADLDPTDPYVD------KEMRKLQQIGADIEAWESQAA 1118
            ..|..|:.|..:                  |..||.|:      |:.:|||
Zfish   524 ALRGGGVEEIKA------------------DFQDPPVENGEKKKKKKKKLQ-------------- 556

  Fly  1119 KYFRRLTQQHELGEIEQFLKSASDI----NGQVP-------------------SHGLLKDALRKA 1160
                 ||.:....|:.:...:||::    ||..|                   .|.:.|..:|..
Zfish   557 -----LTDEMSFQEVFEQFTTASEMQNQSNGAAPLQTNPFTKLKKKVEVKKSRRHPISKPPMRSP 616

  Fly  1161 REWLRAVEQLQQNNHVTYCHTLEAMIERGLNIPIQLEELSRMQGHLNSAHQWKDNTACAFLKKGT 1225
            ..   .|:|...::...|         .||.:...:...|:..   ..:..|: |.:..||.:..
Zfish   617 HS---IVKQEASSDEELY---------SGLPVGGGVTHESKKP---EDSDLWQ-NRSPNFLAEKQ 665

  Fly  1226 FYTLLEVLMPRSDAINIDSDLKPRFQDDFLKEKNPAEIVASFKHAEEQELLDMREL-RRQNMNKN 1289
            |...:..:.|......:........:|.|                   .:.||..| .|......
Zfish   666 FNAAMSTIEPYCAICTLFCPYTQSVKDPF-------------------HISDMSGLVSRVGCRTR 711

  Fly  1290 PMRDMFCL---------------CKSEFRNLMFNCQLCRDWFHEDCVPPPSATNQNGIVNGGSGP 1339
            |:....|.               ...:..:::.:|..|....|..|.              |..|
Zfish   712 PLVPEMCFSAGAENMEPLSSNSHIADDGTSVLLSCSGCNLQVHASCY--------------GVNP 762

  Fly  1340 GTNRPKWLCPSC 1351
            .|.:..|:|..|
Zfish   763 QTKQEGWMCSRC 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lid	NP_001245908.1	JmjN	160..201	CDD:128818
		ARID	227..312	CDD:198082	1/2 (50%)
		PHD1_Lid_like	450..495	CDD:277078	6/44 (14%)
		JmjC	624..740	CDD:202224	48/115 (42%)
		zf-C5HC2	830..882	CDD:280996	4/51 (8%)
		PLU-1	896..1229	CDD:285609	62/365 (17%)
		PHD2_KDM5A	1295..1351	CDD:277079	10/70 (14%)
		PHD3_KDM5A_like	1755..1805	CDD:277083
kdm4b	NP_001076274.1	JmjN	95..136	CDD:128818	16/100 (16%)
		JmjC	256..372	CDD:202224	48/115 (42%)
		YscO	<408..512	CDD:284686	31/248 (13%)
		PHD_JMJD2B	676..774	CDD:277051	17/130 (13%)
		PHD_SF	783..892	CDD:304600
		TUDOR	905..953	CDD:197660
		tatB	<978..1099	CDD:166942

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586201
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840