DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lid and ATPsynbetaL

DIOPT Version :9

Sequence 1:	NP_001245908.1	Gene:	lid / 33837	FlyBaseID:	FBgn0031759	Length:	1838	Species:	Drosophila melanogaster
Sequence 2:	NP_648836.2	Gene:	ATPsynbetaL / 39761	FlyBaseID:	FBgn0036568	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	46/257 - (17%)
Similarity:	88/257 - (34%)	Gaps:	70/257 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1425 GAGVGNISSPRKPRRRGSLTK-------------EASGSTESDADDDD---------------DE 1461
            |..:|.:.......|.||:|.             .|..:|.|..|...               |.
  Fly   380 GTDMGTMQERITSTRNGSITSVQAVYVPADDLSDPAPAATFSHLDATTVLSRPIAELGIYPAVDP 444

  Fly  1462 DECRLRIVEDNFSNDEDEPRTAPATSTVNS-----DLLKLLSDSEIENLLDLMMEGDLLEVS--- 1518
            .:...||::.:...:|..........|:.:     |::.:|.       :|.:.|.|.|.|:
  Fly   445 LDSSSRILDPDVVGEEHYNVARAVQKTLQAYKSLQDIIAILG-------MDELSEEDKLTVARAR 502

  Fly  1519 -----LDETQELWRILETMPPTLLQAEAMERVVQYMQRQRQQHTNPLP------TSGAEDSNDSL 1572
                 |.:..::..|....|..|:   .:|:.|:..:|......:.:|      ...||:    :
  Fly   503 KMQRFLSQPFQVAEIFTGHPGKLV---PVEKCVEGFKRLLNGEYDDIPEIAFYMVGDAEE----V 560

  Fly  1573 MVQNSPNSNSNSGGATGSASNSGRNKKRRSNDTGGNSAVPRK--------KQSTPKQTPGKK 1626
            :.:.:..:.|.||.|..:.:.:.:::|:.:....|....|.|        |...||: |.||
  Fly   561 LAKATQLAASMSGDAPPAKAEAKKDEKKDTKPEEGKKEEPPKGEDKKEEAKDDKPKE-PEKK 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lid	NP_001245908.1	JmjN	160..201	CDD:128818
		ARID	227..312	CDD:198082
		PHD1_Lid_like	450..495	CDD:277078
		JmjC	624..740	CDD:202224
		zf-C5HC2	830..882	CDD:280996
		PLU-1	896..1229	CDD:285609
		PHD2_KDM5A	1295..1351	CDD:277079
		PHD3_KDM5A_like	1755..1805	CDD:277083
ATPsynbetaL	NP_648836.2	PRK09280	103..568	CDD:236447	32/201 (16%)
		ATP-synt_ab_N	106..173	CDD:280947
		F1-ATPase_beta	175..454	CDD:238553	13/73 (18%)
		ATP-synt_ab_C	462..571	CDD:278722	18/122 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900