back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lid and KDM4E

DIOPT Version :9

Sequence 1:	NP_001245908.1	Gene:	lid / 33837	FlyBaseID:	FBgn0031759	Length:	1838	Species:	Drosophila melanogaster
Sequence 2:	NP_001155102.1	Gene:	KDM4E / 390245	HGNCID:	37098	Length:	506	Species:	Homo sapiens

Alignment Length:	351	Identity:	108/351 - (30%)
Similarity:	159/351 - (45%)	Gaps:	48/351 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 IPKGEWLCPRCV-----------VEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH 538
            ||..||...:..           :::|:..|... |.|..::....:.||.......:.::.|.|
Human    49 IPPKEWKARQMYDDIEDILIATPLQQVTSGQGGV-FTQYHKKKKAMRVGQYRRLANSKKYQTPPH 112

  Fly   539 LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYLLPGDQEYAESSWNLNNLP 603
            ....:: |:.:|:   |...:..: ||||:      ||     ||:      |.:...|||.:|.
Human   113 QNFADL-EQRYWK---SHPGNPPI-YGADI------SG-----SLF------EESTKQWNLGHLG 155

  Fly   604 LLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQF 668
            .:.|.:.......|.|:|.|::|.||....|.||.||...|||||||:|||||||.||....:..
Human   156 TILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHL 220

  Fly   669 EETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYN 733
            |...::..|::.......|...|.:::|.:|..|.:|.....|.||||::|||..||||||.|:|
Human   221 ERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFN 285

  Fly   734 FAEAVNFAPADWL---KMGRECVNHYSMLRRFCVFSHDELVCKMALEPAKLTFGIATACYIDMAE 795
            .|||:|||...|:   ||..:|    |.......||.|..|..:..|..:|     .....|:|.
Human   286 CAEAINFATPRWIDYGKMASQC----SCGESTVTFSMDPFVRIVQPESYEL-----WKHRQDLAI 341

  Fly   796 MVDTEKKLRKS--LLEWGVTRAERRA 819
            :..||.::.:|  |..|......|||
Human   342 VEHTEPRVAESQELSNWRDDIVLRRA 367

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.