Protein Alignment Kdm5 and Kdm4B

DIOPT Version :10

• Sequence 1: NP_523486.1
• Gene: Kdm5 / 33837
• FlyBaseID: FBgn0031759
• Length: 1838
• Species: Drosophila melanogaster
• Sequence 2: NP_001260942.1
• Gene: Kdm4B / 318918
• FlyBaseID: FBgn0053182
• Length: 717
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 102/309 - (33%)
• Similarity: 149/309 - (48%)
• Gaps: 55/309 - (17%)

  Fly   485 IPKGEWL---------------CPRCVVEEVSKPQEAFGFEQ----AEREYTLQQFGQMADQFKQ 530
            :|..||:               .|..:.:.|:..|   |:.|    .::..|::||.::|   ..
  Fly    43 VPPPEWVPRRSGYADLDALNVTIPAPICQVVTGKQ---GYYQQINIQKKPLTVKQFSELA---ST 101

  Fly   531 EYFRKPVHLVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYLLPGDQEYAES 595
            |.:..|.|. ..|.:||::|:.::.    |...||||:      ||..|.:       ||:
  Fly   102 ERYATPKHF-DFEDLERKYWKNITY----VAPIYGADV------SGSITDT-------DQD---- 144

  Fly   596 SWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGV 660
            |||:|.|..:.|.:....|..|.|:|..::|.||....|.||.||...|||||||:|.|||||.|
  Fly   145 SWNINRLGTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYVV 209

  Fly   661 PGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYH 725
            |..|..:.|:...|..|..:.:....|...:|:::|.||..:.|||.:..|.|||.:||||..||
  Fly   210 PPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQHDVPVSKITQEAGEIMITFPFGYH 274

  Fly   726 AGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKM 774
            ||||.|:|.||:.|||...|::.|:..|.        |..|:|.:...|
  Fly   275 AGFNHGFNCAESTNFAMERWIEYGKRAVQ--------CTCSNDMVKISM 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm5	NP_523486.1	JmjN	160..201	CDD:128818
		ARID_JARID	226..312	CDD:350628
		PHD1_Lid_like	450..495	CDD:277078	4/24 (17%)
		JmjC	624..740	CDD:396791	53/115 (46%)
		zf-C5HC2	830..882	CDD:460750
		PLU-1	896..1231	CDD:462475
		PHD2_KDM5A	1295..1351	CDD:277079
		PHD3_KDM5A_like	1755..1805	CDD:277083
Kdm4B	NP_001260942.1	JmjN	5..50	CDD:128818	3/6 (50%)
		JmjC	173..289	CDD:396791	53/115 (46%)