Protein Alignment lid and utx-1

DIOPT Version :9

• Sequence 1: NP_001245908.1
• Gene: lid / 33837
• FlyBaseID: FBgn0031759
• Length: 1838
• Species: Drosophila melanogaster
• Sequence 2: NP_001309685.1
• Gene: utx-1 / 181110
• WormBaseID: WBGene00017046
• Length: 1146
• Species: Caenorhabditis elegans
• Alignment Length: 1019
• Identity: 197/1019 - (19%)
• Similarity: 333/1019 - (32%)
• Gaps: 352/1019 - (34%)

  Fly   721 PRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSM--LRRFCVFSHDELVCKMALEPAKLTF 783
            |...|.|     ||.:        ||::  ..:.:|.:  :|.....|.||...:   .||.||:
 Worm    18 PEERHPG-----NFKK--------WLEL--PLLTNYELERIRTLSSLSFDEFHVQ---NPADLTY 64

  Fly   784 GIA---------TACYID-MAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCF 838
            .:.         ...|:| |..:..|.|  .|::        |||.|
 Worm    65 QVRLFFAKARQYLVRYVDEMKSIYKTHK--YKTI--------ERRIF------------------ 101

  Fly   839 LSAVACECNDKLIV------------CLRHYTVLCGCAPEKH---TLIYRYTLDEMPLMLQKLKV 888
             ..:|.:|:..|:.            .|.|:..|....|..:   .|:|.:
 Worm   102 -YGLAKQCHVVLLANDWTGALELYQEVLSHHPDLFSHDPSMYFGLGLVYLH-------------- 151

  Fly   889 KAHSFERWLSRCRDIVDAHTPTSVTLQELQELCKEAETKKFPSSLLI----DRLNAAAVEAE--- 946
                |::|    :..::|.|....:               ||:.::.    .||....:|.|
 Worm   152 ----FKQW----KPAIEAFTRLLYS---------------FPTGMIALQAKVRLGVCYMELEDYN 193

  Fly   947 KCVTVIQQLGINKVRTRSDHNQEAAQYKLTME-ELELFVQEIDNLCCIIDEGASVRELLVLGKQF 1010
            :|:.:. :|.:|      |.::.....|.|:: .:.|..:..|.|
 Worm   194 RCINLF-KLAVN------DSDESVFMPKFTIKYNIALSHENNDEL-------------------- 231

  Fly  1011 VERSESQLQLSLESLEESELETLINE--------GSSLRIELQQLDLL----QKRLKQCKW--YK 1061
                         .:.|||.|.||.|        .|...::.||:|||    ...|:|..|  |:
 Worm   232 -------------EIAESEYENLITELTQHISFLQSKSNVDQQQVDLLISVKAACLRQIGWISYR 283

  Fly  1062 RSQGLRETSSKLTYQDVKNLLH---------IAAADLDPTDPYVDKEMRKLQQIGADIEAWESQA 1117
            ||           |:|..|.|.         |:|.|.||.|                     .|:
 Worm   284 RS-----------YKDDANRLDHLKKAQENLISAHDTDPRD---------------------GQS 316

  Fly  1118 AKYFRRLTQQHELGEIEQFLKSASDINGQVPSHGLLKDALRKAREWLRAVEQLQQNNHVTYCHTL 1182
            ..|..|:..:||           ..::||| :|    ||....|   .::::.:||.. |:| ::
 Worm   317 YYYLGRVYGEHE-----------PSVSGQV-AH----DAFVNYR---FSIDKKEQNAD-TWC-SI 360

  Fly  1183 EAMIERGLNIPIQLEELSRMQGHLNSAHQ--WKDNTACAFLKKGTFYTLLEVLMPRSDAIN---I 1242
            .|:.:| .|.||...:.......|||.|.  |.| ....:.|...:...||..  ::..:|   .
 Worm   361 GALYQR-QNQPIDALQAFICAIELNSTHSAAWTD-LGELYEKNAQYQDALECF--KNAMLNNPVA 421

  Fly  1243 DSDLKPRFQDDFLKEK----------NPAE------IVASFKHAEEQEL-LDMRELR------RQ 1284
            ...:|.|.|  ||:::          |.|.      ::.|.|.|.||.: |::|..:      |:
 Worm   422 PEPIKARVQ--FLEKELSMPVPARPSNHASSSTFETVIPSLKEAYEQPIPLELRNRQDAAYADRE 484

  Fly  1285 NMNKNPMRDMFCLCKSEFRNLMFNCQLCRDWFHEDCVPPPSATNQNGIVN--GGSGPGTNRPKWL 1347
            ....|...|::    .:||.:........:|  :...|.|....:..::.  ..:.|...:.:..
 Worm   485 AQYDNAFWDLW----EDFRTMEHEKPEDMEW--DVTYPRPMEDLEIQVMQLLRANEPALVKAERE 543

  Fly  1348 CPSCVRS-----KRPRLETILPLLVQLQQLPIRLPED------------EALRC-----LAERAM 1390
            ...|:.:     |...:|.::|..|  :::| |:.|:            |:.||     |.:.:.
 Worm   544 VLECLETSEAVFKAKVIEYVIPEAV--REMP-RVTEEMIQNLRDHGHLLESPRCYSFPFLPKISF 605

  Fly  1391 NWQDRARKALS----SPDVSAAQEAIMAQQQQKRRSEGGAGVGNI-----SSPRKPRRRGSLTKE 1446
            |....:...||    |.|:||  :.||  |...||::..:....:     ..|..||
 Worm   606 NDLPDSFSLLSELYVSMDISA--QEIM--QMVHRRTQPNSTYLPVFEEFAKLPEPPR-------- 658

  Fly  1447 ASGSTESDADDDDDEDECRLRIVEDNFSNDEDEP--RTAPATSTVNS------DLLKLLSDSEIE 1503
              |..:....|:|         |.......|..|  ...|..:..|.      :|.:.|..|.|.
 Worm   659 --GPVKPIVTDED---------VRTALERSEKHPLILKTPILTVDNRKEAQSLELQRFLDGSTIS 712

  Fly  1504 NL--------LDLMMEGDLLEVSLDETQEL-WRILETMPPTLLQAEAMERVVQYMQRQRQQHTNP 1559
            .:        |||.:........:|..||: .|....:||......|.::..|.:........|.
 Worm   713 CIRGLTGCLRLDLSLFSTKAVAEIDGNQEIEIRTQYQLPPETNCDHASQQTWQCVSDPSYTTVNK 777

  Fly  1560 LPTSGAEDSNDSLMVQNSPNSNSNSGGATGSASNSGRNKKRRSN 1603
            .....:|....:|..: :.....|.||..|.:....:..||.|:
 Worm   778 YAEYQSESFKHTLKGE-AEKIKKNVGGTRGPSPKRMKLYKRASS 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lid	NP_001245908.1	JmjN	160..201	CDD:128818
		ARID	227..312	CDD:198082
		PHD1_Lid_like	450..495	CDD:277078
		JmjC	624..740	CDD:202224	5/18 (28%)
		zf-C5HC2	830..882	CDD:280996	9/66 (14%)
		PLU-1	896..1229	CDD:285609	75/365 (21%)
		PHD2_KDM5A	1295..1351	CDD:277079	6/57 (11%)
		PHD3_KDM5A_like	1755..1805	CDD:277083
utx-1	NP_001309685.1	TPR_11	138..204	CDD:290150	15/103 (15%)
		TPR repeat	138..168	CDD:276809	7/51 (14%)
		TPR repeat	176..203	CDD:276809	6/27 (22%)
		TPR repeat	271..301	CDD:276809	10/40 (25%)
		TPR repeat	315..348	CDD:276809	12/51 (24%)
		TPR_11	353..419	CDD:290150	18/71 (25%)
		TPR repeat	353..383	CDD:276809	8/32 (25%)
		TPR_1	354..387	CDD:278916	10/35 (29%)
		TPR repeat	388..415	CDD:276809	5/29 (17%)
		TPR	390..419	CDD:197478	6/31 (19%)
		JmjC	845..909	CDD:214721
		JmjC	879..987	CDD:202224

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900