DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ifc and DES-1-LIKE

DIOPT Version :9

Sequence 1:	NP_476594.1	Gene:	ifc / 33836	FlyBaseID:	FBgn0001941	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_192402.1	Gene:	DES-1-LIKE / 825832	AraportID:	AT4G04930	Length:	332	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	166/314 - (52%)
Similarity:	221/314 - (70%)	Gaps:	8/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VSRTDFEWVYTEEPHASRRKIILEKYPQIKKLFGHDPNFKWVAGAMVLTQILAL---FVVKDLSW 66
            |..|||.|.||:|||||||:.||..||||::|||.||   |....:.|..||.|   .::.:..|
plant    19 VMATDFFWSYTDEPHASRRRQILSCYPQIRQLFGPDP---WAFLKITLVVILQLSTAAILHNSGW 80

  Fly    67 SWLIVAAYCFGGIINHSLMLAVHEISHNLAFGHSRPMHNRILGFICNLPIGLPMSISFKKYHLEH 131
            ..::..||.||..:||:|.||:||:||||||  |.|::||.||...|||||:|||::|:||||||
plant    81 LKILSIAYFFGSFLNHNLFLAIHELSHNLAF--STPVYNRCLGIFANLPIGVPMSVTFQKYHLEH 143

  Fly   132 HRYQGDEAIDTDIPTLLEARLFDTTFGKFLWVCLQPFFYIFRPLIINPKPPTRLEIINTVVQLTF 196
            ||:||.:.||.|:||..||.|....|.|.:||.||.|||..||:.|.||||...|.||.::|:..
plant   144 HRFQGVDGIDMDVPTYTEAHLVTNIFAKTIWVFLQLFFYALRPIFIKPKPPGYWEFINFLIQIVL 208

  Fly   197 NALIVYFLGWKPLAYLLIGSILAMGLHPVAGHFISEHYMFAKGFETYSYYGPLNWITFNVGYHNE 261
            :..:|.|.||:..|||::.:.:..|:||:|||||||||:|....||||||||||.:|::||||||
plant   209 DVSVVLFFGWRSFAYLILSTFVGGGMHPMAGHFISEHYVFNPNQETYSYYGPLNLLTWSVGYHNE 273

  Fly   262 HHDFPAVPGSRLPEVKRIAKEFYDTMPQHTSWTRVLYDFIMDPAVGPYARVKRR 315
            |||||.:||::|..||.||.|:|:.:..:.||::|:|.:|||..||||:|:||:
plant   274 HHDFPRIPGNKLHLVKEIAGEYYEGLESYKSWSQVIYMYIMDTTVGPYSRMKRK 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ifc	NP_476594.1	PLN02579	3..315	CDD:215316	165/312 (53%)
		Lipid_DES	6..42	CDD:285726	23/35 (66%)
		Delta4-sphingolipid-FADS-like	26..315	CDD:239585	151/291 (52%)
DES-1-LIKE	NP_192402.1	PLN02579	11..332	CDD:215316	166/314 (53%)
		Lipid_DES	22..56	CDD:285726	24/36 (67%)
		Delta4-sphingolipid-FADS-like	40..327	CDD:239585	151/291 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	272	1.000	Domainoid score	I436
eggNOG	1	0.900	-	-		E1_KOG2987
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23617
Inparanoid	1	1.050	358	1.000	Inparanoid score	I600
OMA	1	1.010	-	-		QHG53934
OrthoDB	1	1.010	-	-		D1255438at2759
OrthoFinder	1	1.000	-	-		FOG0001222
OrthoInspector	1	1.000	-	-		oto2852
orthoMCL	1	0.900	-	-		OOG6_101167
Panther	1	1.100	-	-	LDO	PTHR12879
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X762
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840