DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ifc and ttm-5

DIOPT Version :9

Sequence 1:	NP_476594.1	Gene:	ifc / 33836	FlyBaseID:	FBgn0001941	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_493549.1	Gene:	ttm-5 / 173327	WormBaseID:	WBGene00013197	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	175/317 - (55%)
Similarity:	239/317 - (75%)	Gaps:	0/317 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGQKVSRTDFEWVYTEEPHASRRKIILEKYPQIKKLFGHDPNFKWVAGAMVLTQILALFVVKDLS 65
            |||.|||.||.|..||:||.|||:.|::|||::|||||.||:.|:|..::|:.||...::::|..
Worm     1 MGQSVSRDDFIWTLTEQPHMSRREEIVKKYPEVKKLFGVDPSLKYVVSSLVIFQIFMCWLLQDAD 65

  Fly    66 WSWLIVAAYCFGGIINHSLMLAVHEISHNLAFGHSRPMHNRILGFICNLPIGLPMSISFKKYHLE 130
            |..:|:.||..||||||::.||:|:||||.|||:..|:.||..|...||||.:|:|:||||||:|
Worm    66 WILIILEAYFCGGIINHAMTLAIHDISHNTAFGNKYPLKNRFFGMWANLPIAVPISVSFKKYHVE 130

  Fly   131 HHRYQGDEAIDTDIPTLLEARLFDTTFGKFLWVCLQPFFYIFRPLIINPKPPTRLEIINTVVQLT 195
            ||||.|::.:|||:||..||..|.|...|.||:.||||||.||||||..|.||.:||:|.::|::
Worm   131 HHRYLGEDGLDTDVPTTFEAEFFTTAPRKLLWLALQPFFYGFRPLIIYKKAPTDMEILNAIIQIS 195

  Fly   196 FNALIVYFLGWKPLAYLLIGSILAMGLHPVAGHFISEHYMFAKGFETYSYYGPLNWITFNVGYHN 260
            |:.||::|.|.|.|.|||.|:|::|||||.|||||||||.|.:..||:||||..|..|||||||.
Worm   196 FDLLILHFFGVKSLFYLLFGTIISMGLHPSAGHFISEHYAFKEDQETFSYYGLWNLCTFNVGYHV 260

  Fly   261 EHHDFPAVPGSRLPEVKRIAKEFYDTMPQHTSWTRVLYDFIMDPAVGPYARVKRRQR 317
            ||||||.:||..||:::.:|.|:|:.:.:|||..::|.:|:::||:|||||:||:.|
Worm   261 EHHDFPYIPGRDLPKLRAMAPEYYENLLKHTSMMQILTEFVVNPAMGPYARLKRKPR 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ifc	NP_476594.1	PLN02579	3..315	CDD:215316	171/311 (55%)
		Lipid_DES	6..42	CDD:285726	22/35 (63%)
		Delta4-sphingolipid-FADS-like	26..315	CDD:239585	157/288 (55%)
ttm-5	NP_493549.1	PLN02579	3..316	CDD:215316	172/312 (55%)
		Lipid_DES	6..41	CDD:285726	21/34 (62%)
		Delta4-sphingolipid-FADS-like	26..315	CDD:239585	157/288 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166764
Domainoid	1	1.000	280	1.000	Domainoid score	I889
eggNOG	1	0.900	-	-		E1_KOG2987
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23617
Inparanoid	1	1.050	390	1.000	Inparanoid score	I1140
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53934
OrthoDB	1	1.010	-	-		D1255438at2759
OrthoFinder	1	1.000	-	-		FOG0001222
OrthoInspector	1	1.000	-	-		otm14351
orthoMCL	1	0.900	-	-		OOG6_101167
Panther	1	1.100	-	-	LDO	PTHR12879
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R304
SonicParanoid	1	1.000	-	-		X762
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800