Protein Alignment eIF4A and FAL1

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_010304.3
• Gene: FAL1 / 851584
• SGDID: S000002428
• Length: 399
• Species: Saccharomyces cerevisiae
• Alignment Length: 379
• Identity: 229/379 - (60%)
• Similarity: 294/379 - (77%)
• Gaps: 3/379 - (0%)

  Fly    27 EVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQ 91
            :|...|:.|||:::||||||.||||.||:||.|||...:.|:||||||||||||||||:|.:||.
Yeast    20 KVSSTFESMNLKDDLLRGIYSYGFEAPSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQA 84

  Fly    92 IDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILES-GCHVVVGT 155
            ||...::.|||||:||||||:||.:||..||:||.|::.|..||..:::|.:.::. ||..|.||
Yeast    85 IDLRKKDLQALILSPTRELASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGT 149

  Fly   156 PGRVYDMINRKVLRTQYIKLFVLDEADEMLSR--GFKDQIQDVFKMLPPDVQVILLSATMPPDVL 218
            ||||.|||.:::|:|:.:::.|||||||:||.  |||.||.|:|..||.:.||:::||||..|:|
Yeast   150 PGRVLDMIKKQMLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDIL 214

  Fly   219 EVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVD 283
            ||:|.||.|||.||||::|::||||||:.|||.:|.||..||||:||:|:|||.||||||::|||
Yeast   215 EVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKKKVD 279

  Fly   284 QLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPS 348
            .|:|.:...||.|.:|||||:|.:|:.:|..||:|.|||||:||:.||||||||||||||||||.
Yeast   280 WLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPE 344

  Fly   349 NRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADL 402
            ..|||||||||.||||||||||||||..|...|::||:||...|..||||.|:|
Yeast   345 IIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMPANFAEL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	229/379 (60%)
		DEADc	32..232	CDD:238167	115/202 (57%)
		Helicase_C	254..358	CDD:278689	68/103 (66%)
FAL1	NP_010304.3	PTZ00424	20..398	CDD:185609	228/377 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53631
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		otm46938
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X250
TreeFam	1	0.960	-	-
	6	5.880