Protein Alignment eIF4A and Eif4a3l1

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001136206.1
• Gene: Eif4a3l1 / 668137
• MGIID: 3644226
• Length: 411
• Species: Mus musculus
• Alignment Length: 399
• Identity: 266/399 - (66%)
• Similarity: 326/399 - (81%)
• Gaps: 7/399 - (1%)

  Fly     7 IPQDGPASMEPEGVIESTWHEV--YDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRD 69
            :.:||...:|.|     |..||  ...||.|.|||:||||||.||||||||||||||...::|||
Mouse    18 LKEDGMTKVEFE-----TSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRD 77

  Fly    70 VIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIG 134
            ||||:||||||||||||::||.:|..:||.||||||||||||.|||:.::|||:||.|..|||:|
Mouse    78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVG 142

  Fly   135 GTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKM 199
            ||||.||.|.|:.|.|||.||||||:|||.|:.|.|:.||:.|||||||||:||||:||.||::.
Mouse   143 GTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRY 207

  Fly   200 LPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLY 264
            |||..||:|:|||:|.::||::..||..|:.||||::||||||||||:|.|::|.||..||||||
Mouse   208 LPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY 272

  Fly   265 DTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLL 329
            |||:|||:||||.|:||||.||::|...|||||:|||||.|::||.|||:||||:|||||:||:.
Mouse   273 DTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337

  Fly   330 ARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEE 394
            |||:||.||||:||||||:|||.|||||||.||:|||||||||:.:||.|||:||||:|.|.|:|
Mouse   338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDE 402

  Fly   395 MPANIADLI 403
            ||.|:||||
Mouse   403 MPMNLADLI 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	264/397 (66%)
		DEADc	32..232	CDD:238167	133/199 (67%)
		Helicase_C	254..358	CDD:278689	75/103 (73%)
Eif4a3l1	NP_001136206.1	PTZ00424	22..411	CDD:185609	263/393 (67%)
		DEADc	40..240	CDD:238167	133/199 (67%)
		HELICc	251..380	CDD:238034	94/128 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53631
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X250
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920