Protein Alignment eIF4A and Dbp73D

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Alignment Length: 465
• Identity: 118/465 - (25%)
• Similarity: 198/465 - (42%)
• Gaps: 120/465 - (25%)

  Fly    14 SMEPEGVIESTWHEVYDNFDDMN------LREELLRGIYGYGFEK---PSAIQQRAIIPCVRGRD 69
            |::||..:.::  |..|..|.:.      |::..::.:  :..:|   |..::..|..|..|.||
  Fly   125 SLQPEEEVPAS--EAIDQLDYLEKYTCQALKQMKIKRL--FPVQKQVIPWILEAHAKPPPFRPRD 185

  Fly    70 VIAQAQSGTGKTATFSIAIL----QQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSH 130
            :...|.:|:|||..|:|.|:    |::|..:|   ||::.|..|||.|:.||:..|  ..|....
  Fly   186 ICVSAPTGSGKTLAFAIPIVQLLSQRVDCKVR---ALVVLPVAELALQVYRVISEL--CSKTELE 245

  Fly   131 ACIGGTNVR---EDARILE-------SGCHVVVGTPGRVYDMIN-RKVLRTQYIKLFVLDEADEM 184
            .|:.....:   |..:::|       |...:||.||||:.|.:: .|....:.:|..|:||||.:
  Fly   246 VCLLSKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRI 310

  Fly   185 LSRGFKD---------------------------QIQDVFKMLPPDVQVILLSATM--PPDVLEV 220
            :...|::                           ::|..|...|   ..:|.|||:  .|:.|:.
  Fly   311 MDAVFQNWLYHLDSHVKETTDQLLAGTQAPLCYAELQASFGKQP---HKLLFSATLSQDPEKLQD 372

  Fly   221 SRCF-------------MRDPVSILVKKEELTLEG------------IKQFYVN----------- 249
            .|.|             ::|........|.||..|            .:|:.|.
  Fly   373 LRLFQPRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFA 437

  Fly   250 -VKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSI----HNFTVSAMHGDMEQRDRE 309
             |::..|| ..||             |.|:..:..:||..:.:    ::..||.:.|::..:.|.
  Fly   438 LVEKYKWK-RFLC-------------FTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRN 488

  Fly   310 VIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFIT 374
            ..::.|.:|....||.:|.|||||||..|.:|::|:.|.:...||||:||..|.||||.|:..:|
  Fly   489 ERLRDFAAGKINGLICSDALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLT 553

  Fly   375 DDDRRILKDI 384
            :.|..:.|.|
  Fly   554 EQDMTLFKKI 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	118/465 (25%)
		DEADc	32..232	CDD:238167	62/265 (23%)
		Helicase_C	254..358	CDD:278689	32/107 (30%)
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	112/439 (26%)
		DEAD	162..370	CDD:278688	56/215 (26%)
		HELICc	418..551	CDD:238034	43/146 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451791
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030