Protein Alignment eIF4A and CG6418

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_648413.1
• Gene: CG6418 / 39218
• FlyBaseID: FBgn0036104
• Length: 791
• Species: Drosophila melanogaster
• Alignment Length: 393
• Identity: 122/393 - (31%)
• Similarity: 203/393 - (51%)
• Gaps: 37/393 - (9%)

  Fly    11 GPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQ 75
            ||:..:|   :.|..|..:|        |:|::.:....:.:|:.||.:|:...:.|||:|..|:
  Fly   261 GPSPPKP---VTSFGHFGFD--------EQLIKAVRKAEYTQPTPIQAQAVPTALSGRDIIGIAK 314

  Fly    76 SGTGKTATFSIAILQQI---------DTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHA 131
            :|:||||.|...:|..:         |..|    .|||||||||:.||.......|:...::...
  Fly   315 TGSGKTAAFIWPMLMHVMDQKQLKPGDGPI----GLILAPTRELSLQIYNEAKKFGKVYNLNVVC 375

  Fly   132 CIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDV 196
            |.||.:..|.::.||.|..::|.||||:.||:..|....:.:...||||||.|...||:.|::.:
  Fly   376 CYGGGSKWEQSKALEQGAEIIVATPGRMIDMVKMKATNLRRVTFLVLDEADRMFHMGFEPQVRSI 440

  Fly   197 FKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSIL-----VKKEELTLEGIKQFYVNVKQENWK 256
            ...:.||.|.::.|||....:..::|..:.|||.|:     ...:::| :.:..|...:::.||
  Fly   441 CNHVRPDRQCLMFSATFKKRIERLARDVLSDPVRIVQGDLNEANQDIT-QSVYVFPNPLQKWNW- 503

  Fly   257 LGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSR 321
              .||.|...||....:||...:...:.::..:.|..:....:||||:|.||..::.||:.....
  Fly   504 --LLCHLVKFLSEGSVLIFVTKKVDAETVSNNLLIKEYNCLLLHGDMDQADRNKVITQFKRKECD 566

  Fly   322 VLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDR----RILK 382
            :|:.||:.|||:|:..:..|:|||...:.|.:.|||||.||.|.||.|...:||.|:    .:::
  Fly   567 ILVATDVAARGLDIPHIRNVVNYDTARDIETHTHRIGRTGRAGEKGNAYTLVTDKDKEFAGHLVR 631

  Fly   383 DIE 385
            ::|
  Fly   632 NLE 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	122/393 (31%)
		DEADc	32..232	CDD:238167	67/208 (32%)
		Helicase_C	254..358	CDD:278689	33/103 (32%)
CG6418	NP_648413.1	DEADc	271..475	CDD:238167	69/215 (32%)
		DEXDc	284..489	CDD:214692	67/209 (32%)
		Helicase_C	504..609	CDD:278689	36/104 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451734
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940