Protein Alignment eIF4A and CG10077

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001261491.1
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Alignment Length: 410
• Identity: 142/410 - (34%)
• Similarity: 219/410 - (53%)
• Gaps: 28/410 - (6%)

  Fly     5 NEIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRD 69
            |||...|  ...|...||         |::....:.::..|...||.||:|||.:.....:.|||
  Fly   143 NEITIKG--DQVPTPSIE---------FEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRD 196

  Fly    70 VIAQAQSGTGKTATFSIAILQQIDTSIRECQ-----ALILAPTRELATQIQRVVMALGEYMKVHS 129
            ::..||:|:|||..:.:..:..|:...|..:     ||:||||||||.|||:|.:..|....|.:
  Fly   197 LVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRN 261

  Fly   130 HACIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQ 194
            ....||....:.||.||.|..:|:.||||:.|.:.|.....:.....||||||.||..||:.||:
  Fly   262 TCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIR 326

  Fly   195 DVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTL-EGIKQFYVNVKQENWKLG 258
            .:.:.:.||.||::.|||.|.:|.:::..|:.:.:.:.:....|:. ..|.|. |:|..||.||.
  Fly   327 KIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQI-VDVCDENEKLM 390

  Fly   259 TLCDLYDTLSI---TQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSS 320
            .|..|...:|.   |:::||..|:::||::|:.:|...:...|:|||..|::|:.::..||:|..
  Fly   391 KLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRH 455

  Fly   321 RVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFIT-------DDDR 378
            .:|:.||:.|||:||..|..|||||.|||.|:|:|||||.||....|.|....|       :|..
  Fly   456 SILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLI 520

  Fly   379 RILKDIEQFYHTTIEEMPAN 398
            ::|::..|..:..:..|..|
  Fly   521 QVLREANQTINPKLMNMAMN 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	141/409 (34%)
		DEADc	32..232	CDD:238167	72/204 (35%)
		Helicase_C	254..358	CDD:278689	44/106 (42%)
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	142/410 (35%)
		DEADc	159..364	CDD:238167	72/204 (35%)
		HELICc	375..507	CDD:238034	56/132 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840