Protein Alignment eIF4A and Dbp45A

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 122/389 - (31%)
• Similarity: 190/389 - (48%)
• Gaps: 42/389 - (10%)

  Fly    32 FDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSI 96
            |..:.||..|::.:...|.:..:.|||:.|...:.|:|.|..|::|:|||..|::.||:::....
  Fly     9 FQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEP 73

  Fly    97 RECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYD 161
            ....||:|.||.|||.||....:..|:.|.|......|||:...:::.|....|:||..|||:.|
  Fly    74 VSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLAD 138

  Fly   162 -MINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLE------ 219
             :..........:|..|:||||.||:..|.:.:..:.:.||...|.:..||||...:.|
  Fly   139 HLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMKDFIKESSIFPI 203

  Fly   220 VSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSI--------------T 270
            .|.||.....|     :..|:|.:.|.|:           ||..||...:              .
  Fly   204 ASDCFEWSQDS-----DVATVETLDQRYL-----------LCADYDRDMVLIEALRKYREENENA 252

  Fly   271 QSVIFCNTRRKVDQLTQEMSIHNFTVS--AMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 333
            ..:||.||::....|:  |::.|..:.  .:||.|.|::|...:.:|:|...|.||.||:.|||:
  Fly   253 NVMIFTNTKKYCQLLS--MTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGL 315

  Fly   334 DVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAIN-FITDDDRRILKDIEQFYHTTIEEMP 396
            |:..|.||:|:.||...:.||||:||..|.||||::|: |....|..:|..||:..:|.:.|.|
  Fly   316 DIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	122/389 (31%)
Dbp45A	NP_476927.1	SrmB	9..381	CDD:440279	122/389 (31%)