Protein Alignment eIF4A and Dbp45A

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 122/389 - (31%)
• Similarity: 190/389 - (48%)
• Gaps: 42/389 - (10%)

  Fly    32 FDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSI 96
            |..:.||..|::.:...|.:..:.|||:.|...:.|:|.|..|::|:|||..|::.||:::....
  Fly     9 FQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEP 73

  Fly    97 RECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYD 161
            ....||:|.||.|||.||....:..|:.|.|......|||:...:::.|....|:||..|||:.|
  Fly    74 VSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLAD 138

  Fly   162 -MINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLE------ 219
             :..........:|..|:||||.||:..|.:.:..:.:.||...|.:..||||...:.|
  Fly   139 HLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMKDFIKESSIFPI 203

  Fly   220 VSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSI--------------T 270
            .|.||.....|     :..|:|.:.|.|:           ||..||...:              .
  Fly   204 ASDCFEWSQDS-----DVATVETLDQRYL-----------LCADYDRDMVLIEALRKYREENENA 252

  Fly   271 QSVIFCNTRRKVDQLTQEMSIHNFTVS--AMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 333
            ..:||.||::....|:  |::.|..:.  .:||.|.|::|...:.:|:|...|.||.||:.|||:
  Fly   253 NVMIFTNTKKYCQLLS--MTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGL 315

  Fly   334 DVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAIN-FITDDDRRILKDIEQFYHTTIEEMP 396
            |:..|.||:|:.||...:.||||:||..|.||||::|: |....|..:|..||:..:|.:.|.|
  Fly   316 DIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	122/389 (31%)
		DEADc	32..232	CDD:238167	65/206 (32%)
		Helicase_C	254..358	CDD:278689	37/119 (31%)
Dbp45A	NP_476927.1	SrmB	8..490	CDD:223587	122/389 (31%)
		DEADc	9..197	CDD:238167	60/187 (32%)
		Helicase_C	239..346	CDD:278689	36/108 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451695
Domainoid	1	1.000	91	1.000	Domainoid score	I403
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.030