Protein Alignment eIF4A and CG9253

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_610090.1
• Gene: CG9253 / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 388
• Identity: 121/388 - (31%)
• Similarity: 209/388 - (53%)
• Gaps: 5/388 - (1%)

  Fly     2 DDRNEIPQDGPASMEPE---GVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIP 63
            :|.|....|..|::..|   |..:....|....:.|:.|.|.|.:......::.||.||:.||..
  Fly    30 EDNNHKEGDSEAALSGEDDKGSEDDAAEEQKLTWKDLGLNEALCQACDELKWKAPSKIQREAIPV 94

  Fly    64 CVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVH 128
            .::|:|||..|::|:|||..|::.||..:..:.:...||:|.||||||.||.....|||..:.:.
  Fly    95 ALQGKDVIGLAETGSGKTGAFALPILHALLENPQRYFALVLTPTRELAFQIGEQFEALGSGIGIK 159

  Fly   129 SHACIGGTNVREDARILESGCHVVVGTPGRVYDMI-NRKVLRTQYIKLFVLDEADEMLSRGFKDQ 192
            ....:||.::......|....|:::.||||:.|.: |.|....:.||..|:||||.:|:..|:.:
  Fly   160 CCVVVGGMDMVAQGLQLAKKPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVE 224

  Fly   193 IQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKL 257
            :..:.|:||.:.:..|.||||...|.::.|..::|||.:.|..:..|:|.::|.|:.:..: :|.
  Fly   225 LDKILKVLPRERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNKYQTVEQLQQSYLFIPVK-YKD 288

  Fly   258 GTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRV 322
            ..|..:.:.|:....:|||:|.....:....:.........:||.|.|..|...:.:|::.:..:
  Fly   289 VYLVHILNELAGNSFMIFCSTCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSI 353

  Fly   323 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIE 385
            ||:||:.:||:|:..|.:|:|:|:|::.::||||:||..|.||.|.||..::..|..:.:.||
  Fly   354 LISTDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRIE 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	119/384 (31%)
		DEADc	32..232	CDD:238167	69/200 (35%)
		Helicase_C	254..358	CDD:278689	29/103 (28%)
CG9253	NP_610090.1	SrmB	34..498	CDD:223587	119/384 (31%)
		DEADc	63..264	CDD:238167	69/200 (35%)
		HELICc	274..403	CDD:238034	39/129 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940