Protein Alignment eIF4A and CG10333

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Alignment Length: 435
• Identity: 130/435 - (29%)
• Similarity: 215/435 - (49%)
• Gaps: 57/435 - (13%)

  Fly     2 DDRNEIPQDGPASMEPEGVIESTW---HEVYD-------------NFDDMNLREELLRGIYGYGF 50
            |||:.      :..|.:.:.|..|   .|.|:             ::::....:|::..|...|:
  Fly   356 DDRHW------SEKENDEMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGY 414

  Fly    51 EKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDT--SIRECQ-------ALILAP 106
            ::|:.||::||...::.||:|..|::|:|||..|.|.:|..|.:  .|...:       |:|:||
  Fly   415 KEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAP 479

  Fly   107 TRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQ 171
            |||||.||:......|:.:.:.:...:||.:..|....|..||.:|:.||||:.|::..:.|...
  Fly   480 TRELAQQIEEETTKFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLN 544

  Fly   172 YIKLFVLDEADEMLSRGFKDQIQDVFKMLP-----PDV--------------------QVILLSA 211
            .....||||||.|:..||:..:|.:.:.:|     ||.                    |.::.:|
  Fly   545 QCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTA 609

  Fly   212 TMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFC 276
            ||||.|..::|.::|.|.::.:.......|..:|. |.:..||.|...|.::.........:||.
  Fly   610 TMPPAVERLARTYLRRPATVYIGSVGKPTERTEQI-VYMMGENDKRKKLMEILSRKIDPPVIIFV 673

  Fly   277 NTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLV 341
            |.::..|.|.:.:....:....:||...|..||..:...:||:..:|:.||:..||||::.||||
  Fly   674 NQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLV 738

  Fly   342 INYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQ 386
            ||||:....|:|.|||||.||.|:.|.||:|:|.||..:..|::|
  Fly   739 INYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQ 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	127/431 (29%)
		DEADc	32..232	CDD:238167	69/233 (30%)
		Helicase_C	254..358	CDD:278689	34/103 (33%)
CG10333	NP_609888.2	DEADc	396..629	CDD:238167	69/232 (30%)
		DEXDc	409..632	CDD:214692	68/222 (31%)
		Helicase_C	651..761	CDD:278689	39/109 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840