Protein Alignment eIF4A and me31B

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 147/367 - (40%)
• Similarity: 226/367 - (61%)
• Gaps: 2/367 - (0%)

  Fly    30 DNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDT 94
            :.|::..|:.|||.||:..|:|:||.||:.||...:.|:||:|:|::|||||..:.|.:|:|||.
  Fly    58 NEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDP 122

  Fly    95 SIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRV 159
            :....|||::.||||||.|..::.:.|.:::.:......|||.:::|...:.....:::.||||:
  Fly   123 TKDYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKDDILRIYQKVQLIIATPGRI 187

  Fly   160 YDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCF 224
            .|::::||....:.::.||||||::||..|:..:..|...||.|.|::|.|||.|..|.......
  Fly   188 LDLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKH 252

  Fly   225 MRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEM 289
            :|:|..|.: .|||||:|:.|:|..| ||..|:..|..|:..|.|.||:||||:.::|:.|.:::
  Fly   253 LREPYEINL-MEELTLKGVTQYYAFV-QERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKI 315

  Fly   290 SIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYI 354
            :...:....:|..|.|..|..:...||.|..|.|:.:||..||||||.|::|||:|.|...|.|:
  Fly   316 TELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYL 380

  Fly   355 HRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMP 396
            |||||.||||..|:|||.||.:||..|..||:...|.|:.:|
  Fly   381 HRIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	147/367 (40%)
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	147/367 (40%)
		DEADc_DDX6	60..260	CDD:350698	74/199 (37%)