Protein Alignment eIF4A and Hel25E

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 151/390 - (38%)
• Similarity: 234/390 - (60%)
• Gaps: 8/390 - (2%)

  Fly    17 PEGVIESTWHEVYDN-FDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGK 80
            |:..::.|:..::.: |.|..|:.|:||.|...|||.||.:|...|...|.|.|::.||:||.||
  Fly    27 PKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGK 91

  Fly    81 TATFSIAILQQIDTSIRE-CQALILAPTRELATQIQRVVMALGEYM-KVHSHACIGGTNVREDAR 143
            ||.|.:|.|||::.|... |..|::..|||||.||.:......:|| .|......||..:::|..
  Fly    92 TAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEE 156

  Fly   144 ILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSR-GFKDQIQDVFKMLPPDVQV 206
            .|:||. |:|||||||:..:|..|.|..:.:|.|||||.|:||.: ..:..:|::|:..|...||
  Fly   157 TLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQV 221

  Fly   207 ILLSATMPPDVLEVSRCFMRDPVSILVKKE-ELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSIT 270
            ::.|||:..|:..|.:.||:||:.:.|..| :|||.|::|.|||:| ||.|...|.:|.|.|...
  Fly   222 MMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLK-ENEKNKKLFELLDVLEFN 285

  Fly   271 QSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDV 335
            |.|||..:.::...|:|.::..||....:|..|.|.:|....:||:....|:|:.|:|..||:|:
  Fly   286 QVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDI 350

  Fly   336 QQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDD-DRRILKDIEQFYHTTIEEMPANI 399
            ::|::|.|||:|.:.:.|:||:.|.||||.||:||.|::|: |.:||.:::..:...|.|:|..|
  Fly   351 ERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDVNISELPEEI 415

  Fly   400  399
              Fly   416  415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	151/390 (39%)
		DEADc	32..232	CDD:238167	83/203 (41%)
		Helicase_C	254..358	CDD:278689	36/103 (35%)
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	83/207 (40%)
		SF2_C_DEAD	259..388	CDD:350174	51/129 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451365
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840