Protein Alignment eIF4A and Dbp80

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 397
• Identity: 143/397 - (36%)
• Similarity: 231/397 - (58%)
• Gaps: 30/397 - (7%)

  Fly     6 EIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRG--- 67
            :|.|..|         .|..|.| ..|:.::|:..||:|||..||..||.||:.| :|.:..
  Fly    59 DIQQKNP---------NSPLHSV-KTFEALHLKASLLKGIYAMGFNTPSKIQETA-LPTLLADPP 112

  Fly    68 RDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMK-VHSHA 131
            :::|||:||||||||.|.:|:|.:::..:...|.|.|:||.|||.|...|...:|::.: :....
  Fly   113 QNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRF 177

  Fly   132 CIGGTNVREDARILESGCHVVVGTPGRVYDM-INRKVLRTQYIKLFVLDEADEML-SRGFKDQIQ 194
            .:.|..|....:|.|   |:::||||::.|. |..::...:.|.:|||||||.|: ::|..||..
  Fly   178 AVRGEEVDRSKKIEE---HILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCI 239

  Fly   195 DVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGT 259
            .:.|||.|..|::..|||...:|::.:|..:.||..|.:.:||.:||.|||:||..|.|..|...
  Fly   240 RIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNA 304

  Fly   260 LCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLI 324
            :.::|..:|:.|::|||:|:|....|..:|:....:|:.:.||:....|..::.:||||..:|||
  Fly   305 IQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLI 369

  Fly   325 TTDLLARGIDVQQVSLVINYDLP------SNRENYIHRIGRGGRFGRKGVAINF----ITDDDRR 379
            ||::|:||||::||::|:|:|||      ::.|.|:|||||.|||....:..|.    :..:..:
  Fly   370 TTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGK 434

  Fly   380 ILKDIEQ 386
            |.|:|.:
  Fly   435 IGKEINR 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	143/397 (36%)
		DEADc	32..232	CDD:238167	75/205 (37%)
		Helicase_C	254..358	CDD:278689	40/109 (37%)
Dbp80	NP_001263168.1	DEADc	75..277	CDD:238167	75/205 (37%)
		DEXDc	88..291	CDD:214692	77/206 (37%)
		Helicase_C	299..414	CDD:278689	44/114 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840