Protein Alignment eIF4A and Dbp80

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 397
• Identity: 143/397 - (36%)
• Similarity: 231/397 - (58%)
• Gaps: 30/397 - (7%)

  Fly     6 EIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRG--- 67
            :|.|..|         .|..|.| ..|:.::|:..||:|||..||..||.||:.| :|.:..
  Fly    59 DIQQKNP---------NSPLHSV-KTFEALHLKASLLKGIYAMGFNTPSKIQETA-LPTLLADPP 112

  Fly    68 RDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMK-VHSHA 131
            :::|||:||||||||.|.:|:|.:::..:...|.|.|:||.|||.|...|...:|::.: :....
  Fly   113 QNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRF 177

  Fly   132 CIGGTNVREDARILESGCHVVVGTPGRVYDM-INRKVLRTQYIKLFVLDEADEML-SRGFKDQIQ 194
            .:.|..|....:|.|   |:::||||::.|. |..::...:.|.:|||||||.|: ::|..||..
  Fly   178 AVRGEEVDRSKKIEE---HILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCI 239

  Fly   195 DVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGT 259
            .:.|||.|..|::..|||...:|::.:|..:.||..|.:.:||.:||.|||:||..|.|..|...
  Fly   240 RIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNA 304

  Fly   260 LCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLI 324
            :.::|..:|:.|::|||:|:|....|..:|:....:|:.:.||:....|..::.:||||..:|||
  Fly   305 IQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLI 369

  Fly   325 TTDLLARGIDVQQVSLVINYDLP------SNRENYIHRIGRGGRFGRKGVAINF----ITDDDRR 379
            ||::|:||||::||::|:|:|||      ::.|.|:|||||.|||....:..|.    :..:..:
  Fly   370 TTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGK 434

  Fly   380 ILKDIEQ 386
            |.|:|.:
  Fly   435 IGKEINR 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	143/397 (36%)
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	74/200 (37%)
		SF2_C_DEAD	288..414	CDD:350174	51/125 (41%)