Protein Alignment eIF4A and Eif4a2

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_006248596.1
• Gene: Eif4a2 / 303831
• RGDID: 1309225
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 402
• Identity: 293/402 - (72%)
• Similarity: 354/402 - (88%)
• Gaps: 1/402 - (0%)

  Fly     3 DRNEIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRG 67
            |.|.....||..|:|:|||||.|:|:.||||||||:|.||||||.|||||||||||||||||::|
  Rat     7 DYNSREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG 71

  Fly    68 RDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHAC 132
            .||||||||||||||||:|:||||::...:|.|||:||||||||.|||:|::|||:||....|||
  Rat    72 YDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHAC 136

  Fly   133 IGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDV 196
            |||||||.:.:.|::.. |:||||||||:||:||:.|..::||:||||||||||||||||||.::
  Rat   137 IGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEI 201

  Fly   197 FKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLC 261
            |:.|...:||:|||||||.|||||::.|||||:.|||||||||||||||||:||::|.|||.|||
  Rat   202 FQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 266

  Fly   262 DLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITT 326
            |||:||:|||:|||.|||||||.||::|...:|||||:||||:|::|:|||::||||||||||||
  Rat   267 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITT 331

  Fly   327 DLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTT 391
            |||||||||||||||||||||:||||||||||||||||||||||||:|::|:|||:|||.||:||
  Rat   332 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTT 396

  Fly   392 IEEMPANIADLI 403
            :||||.|:||||
  Rat   397 VEEMPMNVADLI 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	289/397 (73%)
Eif4a2	XP_006248596.1	DEAD-like_helicase_N	9..408	CDD:475120	290/398 (73%)